CRISPER Gene Editing
many of you will think that humans are
not perfect
everyone has flaws and many of those
flaws are due to genetic reasons
also many people suffer from genetic
diseases like
hemophilia and huntington’s disease
and we all know that’s not their fault
then is there any way to solve this
problem
well i believe crispr has the key
the nobel prize in chemistry 2020 was
awarded to jointly to emanuel
charpentier
and jennifer a dautna for the
development of
a method for genome editing they
discover
the crispr cast 9 genetic scissors
which is one of gene technology’s
sharpest tools
christopher gene editing has had a
revolutionary
impact on life and is being mentioned as
the key
to curing inherited diseases
from crispr gene editing researchers can
change the dna
of animals plants and microorganisms
with extremely high precision the
technique allows
the deletion addition and
replacement of genetic information
in certain truncated dna parts
some researchers have already developed
car t
on immuno oncology using crispr casting
well now let’s talk more about crispr
why many scientists consider crispr as
an innovation
and the reason it could win the nobel
prize
well before we start we have to know uh
more about
crispr i mean very specifically crispr
refers to a sequence of repetitions
of a short circular structure that is
distributed
at periodic intervals in this sequence a
particular kind of
rna is transferred and that’s grna cas9
grna means guide rna so to put it simply
grna locates the gene like a navigator
and cas9 cuts the gene
at this point when we process the
sequence of grna properly
we can choose where to cut
then what makes crispr so special
compared to other gene editing
technologies well
it’s very easy to control one of the
biggest
reason advantages of this technology is
that
we can easily fix and change the gene
wherever we want this is also the reason
why christopher won the nobel prize
however as much attention
as christopher received there are many
ethical
controversies one of the reasons
christopher hasn’t commercialized
is because we can’t ignore those
controversies
easily in 2018
a chinese scientist ho john koey on the
left
created twin girls resistant to hiv
by editing their genes before their
birth
well the whole world was shocked if gene
editing technology is abused
some people could try to make
a perfect human like the alphas in the
novel brave new world
but since there’s no legal regulations
still many scientists could try to edit
a human ambrose gene
gene editing technology isn’t perfect
yet so
many lives will be sacrificed from this
kind of
experiment
the noble comedy referred to gene
editing gene
genetic scissors as a tool for rewriting
the code of life
this could be interpreted that gene
editing technology is very
powerful but also can be very dangerous
there’s a fine line between those two so
we have to be very careful
when using gene editing technology and
we have to set norms well as quickly as
possible very specific norms to prevent
abuses
thank you for listening