CRISPER Gene Editing

many of you will think that humans are

not perfect

everyone has flaws and many of those

flaws are due to genetic reasons

also many people suffer from genetic

diseases like

hemophilia and huntington’s disease

and we all know that’s not their fault

then is there any way to solve this

problem

well i believe crispr has the key

the nobel prize in chemistry 2020 was

awarded to jointly to emanuel

charpentier

and jennifer a dautna for the

development of

a method for genome editing they

discover

the crispr cast 9 genetic scissors

which is one of gene technology’s

sharpest tools

christopher gene editing has had a

revolutionary

impact on life and is being mentioned as

the key

to curing inherited diseases

from crispr gene editing researchers can

change the dna

of animals plants and microorganisms

with extremely high precision the

technique allows

the deletion addition and

replacement of genetic information

in certain truncated dna parts

some researchers have already developed

car t

on immuno oncology using crispr casting

well now let’s talk more about crispr

why many scientists consider crispr as

an innovation

and the reason it could win the nobel

prize

well before we start we have to know uh

more about

crispr i mean very specifically crispr

refers to a sequence of repetitions

of a short circular structure that is

distributed

at periodic intervals in this sequence a

particular kind of

rna is transferred and that’s grna cas9

grna means guide rna so to put it simply

grna locates the gene like a navigator

and cas9 cuts the gene

at this point when we process the

sequence of grna properly

we can choose where to cut

then what makes crispr so special

compared to other gene editing

technologies well

it’s very easy to control one of the

biggest

reason advantages of this technology is

that

we can easily fix and change the gene

wherever we want this is also the reason

why christopher won the nobel prize

however as much attention

as christopher received there are many

ethical

controversies one of the reasons

christopher hasn’t commercialized

is because we can’t ignore those

controversies

easily in 2018

a chinese scientist ho john koey on the

left

created twin girls resistant to hiv

by editing their genes before their

birth

well the whole world was shocked if gene

editing technology is abused

some people could try to make

a perfect human like the alphas in the

novel brave new world

but since there’s no legal regulations

still many scientists could try to edit

a human ambrose gene

gene editing technology isn’t perfect

yet so

many lives will be sacrificed from this

kind of

experiment

the noble comedy referred to gene

editing gene

genetic scissors as a tool for rewriting

the code of life

this could be interpreted that gene

editing technology is very

powerful but also can be very dangerous

there’s a fine line between those two so

we have to be very careful

when using gene editing technology and

we have to set norms well as quickly as

possible very specific norms to prevent

abuses

thank you for listening