How to stop the next pandemic before it begins

Transcriber: Eunice Tan
Reviewer: Rhonda Jacobs

Who is to blame for the COVID-19 pandemic?

It’s a critical question in the face
of a trillion-dollar catastrophe.

This pandemic was not some act of God;
it wasn’t even unpredictable.

Like many of our most notorious pandemics,

COVID-19 happened primarily because of us,

because of humans,

because of our actions and decisions.

But probably not in the way you think.

It wasn’t engineered
or manufactured in a lab.

It wasn’t caused by the Chinese
government’s attempts to hide the virus

or a failure of leadership in the US.

Those are critical factors on why
we’re experiencing millions of cases,

hundreds and thousands of deaths,
and severe economic and social disruption.

But they didn’t cause
the virus’s emergence.

The virus came from wild animals,

spreading to people because
of our behaviors that put us at risk.

That’s why only we can make sure
this doesn’t happen again.

I’m a conservation biologist
focused on wildlife protection.

Much of my work is concentrated in Africa,
with an emphasis on elephants.

In addition to trying to gain
deeper understanding

of these magnificent creatures,

I work to stop the illegal trade in ivory
that’s decimating the species.

We are putting enormous time,
money, and even human lives

into trying to stop poaching.

But to save elephants,
we need to stop the cause of poaching,

and that’s the demand for ivory.

This recipe is as true for elephants
as it is for diseases.

We need to move beyond treating symptoms
and examine the underlying causes

if we’re to stop outbreaks
from happening in the first place.

So you might be asking yourself,

why am I up here
speaking to you about COVID-19?

Well, it turns out COVID-19
is a zoonotic disease,

meaning it comes from animals to people.

And this is the genesis of the majority
of emerging infectious diseases globally:

HIV, Ebola, even the plague
and Lyme disease,

all of which have
and continue to kill millions.

These diseases jump from animals
to people through interactions,

particularly the exposure
to bodily fluids.

And I’m not talking about

the random stranger that kisses
the mouth of my poop-eating dog,

though that is highly questionable
for so many reasons.

It’s exposure to the blood,
saliva, and feces of animals,

getting bitten or scratched by animals,
and even eating them.

And that might sound shocking,

but it turns out these types of contacts

are happening every day
all over the world,

when we bring thousands
of animals together

as we raise and slaughter livestock,

when we capture, buy, and sell wildlife,

and when we destroy wildlife habitat,

pushing animals towards our cities
in their search for food and shelter.

COVID-19’s notorious epicenter
in Wuhan was a wet market -

this is a grocery store
that sells and slaughters live animals.

And I’m not talking about lobster tanks,

but civet cats and rodents
and all sorts of species

that would normally never come in contact
with each other in the wild.

Yet there they were,

locked in cages
stacked on top of each other,

allowing easy exposure to bodily fluids

and whatever pathogens
they may have been harboring,

all while people were meandering
about nearby, shopping.

These are prime spillover conditions.

And before we point our fingers at China,

I want to be clear that
this is happening all over the world.

We’re all complicit.

In fact, do you want to guess

what is considered to be the number two
destination for illegal wildlife?

It’s the United States of America.

By moving animals around the world
in stressful conditions,

the wildlife trade is a key contributor
to zoonotic disease emergence.

Every step of the commodity chain,
more and more exposure happens

as we bring different species that never
would come in contact in the wild

together,

and humans come in contact
with that strange mix of animals.

This gives pathogens a perfect opportunity

to jump between individuals,
across species, and to us

that naturally would never occur.

A recent study on coronaviruses -

yes, the same family as COVID-19 -

in the live rat trade,
a common food in Vietnam,

found that about 20 percent of rats
were infected at the time of capture.

By the time they were sold to consumers,
55 percent of rats were infected.

The wildlife trade,
by moving animals around,

increases exposure.

The animals that we capture
for the wildlife trade are often weak,

or they become weakened
through the process,

and that makes them
more susceptible to diseases.

Multiple Ebola outbreaks
appear to have begun

when a person found
a disoriented great ape

and captured it.

The poor souls that butchered
and ate that animal

start the outbreak by falling ill,

spreading the disease to their families
and friends and coworkers

as they’re dying.

And this propensity
to capture sick animals is universal.

Here in Colorado,

chronic wasting disease in mule deer,
which is like a mad cow disease for deer,

is found in about one to three percent
of randomly sampled deer in a population,

but 16 percent of harvested bucks.

Luckily, chronic wasting disease
hasn’t jumped to people.

In addition to directly capturing,
trading, and eating animals,

we’re also drawing them to us
by destroying their homes.

By reducing wildlife habitat,

we force animals to move around
in search of new places to live,

and those can often become
our homes or yards or schools.

Nipah virus, on which
the movie “Contagion” was based,

spilled over from bats
after the clearing of native forests,

the bats' homes,

for palm oil plantations -

yes, palm oil -

found in every American grocery store

and products like candy,
Nutella, chips, soaps, and lipsticks.

After losing their forest homes,

the bats moved into
human-dominated landscapes,

and then … spillover.

And Nipah virus has a fatality rate
of up to 75 percent -

far worse than COVID-19.

Again, our actions -

destroying wildlife habitat,
causing animals to move -

is happening all over the world,

from the clearing
of the Brazilian rainforest

to suburban development
right here in Colorado.

One of the best ways
we can prevent the next COVID-19

is to stop the behaviors

that facilitate the transmission
of diseases between species and to us.

Whether we like it or not,

infectious disease emergence
is a game of chance,

not unlike your favorite card game,
say poker or bridge,

but probably more aptly
like Russian roulette.

The animals that we live with, eat,

and fight to keep out
of our homes and our crops -

you know, think about moles
on your golf course -

they’re constantly
exchanging and sharing

viruses and bacteria
and protozoa and fungi with us.

Our actions can amplify or reduce
the odds of spillover.

Given the cost of losing this game,

why aren’t we doing
everything in our power

to tilt the odds in our favor?

Conservationists like myself

have been working to protect wildlife
and their landscapes for decades.

And it turns out
these very conservation goals

are also the actions
that can tilt the odds in our favor.

Ending the global trade
in mammals and birds is a key first step.

The wildlife trade affects all of us,

whether we’re directly buying
and consuming these animals or not.

We need to elect politicians
that take this issue and science seriously

and recognize the fundamentally
critical role the US plays

in global health and disease prevention.

Key individual actions you can take,
beyond not buying ivory or exotic pets,

include buying locally,
eating more plants than animals,

and avoiding products
that lead to deforestation, like palm oil.

Tellingly, my colleagues and I were not
surprised or caught off guard by COVID-19.

Rather, we thought our actions
were making such a pandemic inevitable.

That might be hard to hear,

but given the general apathy
about infectious disease

and the environmental problems
underpinning their emergence,

I think it needs to be said.

The big worry among many

is not the eventual total case
and death count from COVID-19 -

it’s the likelihood that another,
more lethal pathogen spills over.

And not in 10 or 20 years -

right now,

when our attention is subsumed
by the current pandemic.

We are playing the spillover
probability game every day,

and having our full medical diagnostic
development and monitoring capabilities

focus solely on the current pandemic
does not put the odds in our favor.

This pandemic is a wake-up call.

While awful,

it could have been much worse -

the lethality of the first
SARS coronavirus was 10 times higher.

We are pouring
so much energy and heartache

into dealing with
the daily threats of COVID-19.

But we also must focus on the factors

that led to its emergence
in the first place.

Conservation is about more
than just protecting cute animals

and beautiful vistas -

it’s also about protecting us.

COVID-19 has shown us, viscerally,
what can go wrong.

Now is the time for us
to truly invest in our conservation goals,

reduce the odds of spillover,

and make sure we stop
the next pandemic before it even begins.

Thank you.

抄写员:Eunice Tan
审稿人:Rhonda Jacobs

谁应该为 COVID-19 大流行负责?

面对
数万亿美元的灾难,这是一个关键问题。

这种流行病不是上帝的作为。
它甚至不是不可预测的。

像我们许多最臭名昭著的流行病一样,

COVID-19 的发生主要是因为我们,

因为人类,

因为我们的行动和决定。

但可能不是你想的那样。

它不是
在实验室中设计或制造的。

这不是由于中国
政府试图隐瞒病毒

或美国领导力失败造成的。

这些是导致
我们经历数百万病例、

数十万人死亡
以及严重的经济和社会混乱的关键因素。

但它们并没有
导致病毒的出现。

该病毒来自野生动物,

由于我们的行为使我们处于危险之中,因此传播给了人类。

这就是为什么只有我们才能确保
这种情况不会再次发生。

我是一名
专注于野生动物保护的保护生物学家。

我的大部分工作都集中在非洲
,重点是大象。

除了试图
更深入地

了解这些宏伟的生物外,

我还努力制止
正在摧毁该物种的非法象牙贸易。

我们正在投入大量时间、
金钱,甚至是

人命来阻止偷猎。

但是为了拯救大象,
我们需要停止偷猎的事业

,那就是对象牙的需求。

这个食谱对大象
和疾病一样适用。

如果我们要从一开始就阻止疫情
的发生,我们需要超越治疗症状并检查根本原因。

所以你可能会问自己,

我为什么要在这里
和你谈论 COVID-19?

好吧,事实证明 COVID-19
是一种人畜共患病,

这意味着它来自动物到人。

这就是
全球大多数新兴传染病的起源:

艾滋病毒、埃博拉病毒,甚至鼠疫
和莱姆病,

所有这些都已经
并继续导致数百万人死亡。

这些疾病通过相互作用从动物传染
给人类,

尤其是
接触体液。

而且我不是在

谈论随机的陌生人亲吻
我的吃便便的狗的嘴,

尽管出于很多原因,这是非常值得怀疑
的。

它是接触动物的血液、
唾液和粪便,

被动物咬伤或抓伤,
甚至吃掉它们。

这听起来可能令人震惊,

但事实证明,这种类型的接触

每天
都在世界各地发生,

当我们饲养和屠宰牲畜时,

当我们捕捉、购买和出售野生动物

时,当我们将成千上万的动物聚集在一起时,当我们 破坏野生动物栖息地,

将动物推向我们的
城市寻找食物和庇护所。

COVID-19 在武汉臭名昭著的震中
是一个湿货市场——

这是
一家出售和屠宰活体动物的杂货店。

我说的不是龙虾缸,

而是麝香猫和啮齿动物
以及各种

在野外通常不会相互接触的物种。

然而,他们却在那里,被

锁在一个
个堆叠的

笼子里,很容易接触到体液


他们可能藏匿的任何病原体

,而人们却
在附近闲逛,购物。

这些是主要的溢出条件。

在我们将矛头指向中国之前,

我想明确一点,
这种情况正在世界各地发生。

我们都是同谋。

事实上,你想猜猜

非法野生动物的第二大目的地是什么?

这是美利坚合众国。

通过在压力条件下在世界各地移动动物

,野生动物贸易是
人畜共患病出现的关键因素。

商品链的每一步,

随着我们将
在野外永远不会接触的不同物种

聚集在一起

,人类
接触到这种奇怪的动物组合,越来越多的接触发生。

这为病原体提供了一个绝佳的机会,

可以在个体之间、
物种之间以及对我们之间跳跃,而

这自然不会发生。

最近一项关于冠状病毒的研究——

是的,与 COVID-19 属于同一家族——

在越南常见的活鼠贸易
中,

发现大约 20% 的老鼠
在被捕获时被感染。

当它们被卖给消费者时,
55% 的老鼠被感染了。

野生动物贸易
通过移动动物来

增加曝光率。

我们
为野生动物贸易捕获的动物通常很虚弱,

或者它们
在这个过程中变得虚弱

,这使它们
更容易感染疾病。

当一个人发现
一只迷失方向的类人猿

并将其捕获时,似乎已经开始了多次埃博拉病毒的爆发。

屠宰和吃掉那只动物的可怜的灵魂

开始生病,

在他们快要死的时候将疾病传播给他们的家人
、朋友和

同事。

这种
捕捉生病动物的倾向是普遍存在的。

在科罗拉多州,

骡鹿的慢性消耗性疾病
,就像鹿的疯牛病一样,在人群中随机抽样的鹿

中发现了大约 1% 到 3
%,

但在收获的鹿中发现了 16%。

幸运的是,慢性消耗性疾病
并没有传染给人们。

除了直接捕获、
交易和食用动物外,

我们还
通过摧毁它们的家园来吸引它们。

通过减少野生动物栖息地,

我们迫使动物四处移动
以寻找新的居住地,

而这些地方通常会成为
我们的家、院子或学校。

电影“传染病”所依据的尼帕病毒,在

清除原生森林

、蝙蝠的家园

、棕榈油种植园后从蝙蝠身上溢出——

是的,棕榈油——

在每个美国杂货店

和糖果等产品中都有发现,
Nutella、薯片、肥皂和口红。

在失去了他们的森林家园后

,蝙蝠进入了
人类主导的景观,

然后……溢出了。

尼帕病毒的致死
率高达 75%,

远低于 COVID-19。

同样,我们的行动——

破坏野生动物栖息地,
导致动物迁徙——

正在世界各地发生,


巴西热带雨林的清理

到科罗拉多州的郊区开发。

我们可以预防下一个 COVID-19 的最佳方法之一

是停止

促进
疾病在物种之间和我们之间传播的行为。

不管我们喜不喜欢,

传染病的出现
都是一种机会游戏

,与您最喜欢的纸牌游戏(
例如扑克或桥牌)不同,

但可能更贴切地
像俄罗斯轮盘赌。

我们和我们一起生活、吃东西、

为了
远离我们的家园和庄稼而奋斗的动物——

你知道,想想
你高尔夫球场上的鼹鼠——

它们不断地与我们
交换和分享

病毒、细菌
、原生动物和真菌。

我们的行动可以扩大或减少
溢出的可能性。

考虑到输掉这场比赛的代价,

我们为什么不竭尽全力

让胜算对我们有利呢? 几十年来,

像我

这样的环保主义者一直致力于保护野生动物
及其景观。

事实证明,
这些非常保护目标

也是
可以使我们的胜算倾斜的行动。

结束
哺乳动物和鸟类的全球贸易是关键的第一步。

野生动物贸易影响着我们所有人,

无论我们是否直接购买
和消费这些动物。

我们需要选出
认真对待这个问题和科学

并认识
到美国

在全球健康和疾病预防中所发挥的根本性关键作用的政治家。

除了不购买象牙或异国情调的宠物外,您可以采取的关键个人行动

包括在当地购买、
食用比动物更多的植物

以及避免使用
会导致森林砍伐的产品,例如棕榈油。

很明显,我和我的同事
对 COVID-19 并不感到惊讶或措手不及。

相反,我们认为我们的
行动使这种流行病不可避免。

这可能很难听到,

但考虑到对传染病的普遍冷漠

以及
支撑它们出现的环境问题,

我认为有必要说出来。

许多人

最担心的不是 COVID-19 的最终病例总数
和死亡人数——

而是另一种
更致命的病原体溢出的可能性。

而不是在 10 年或 20 年后——

现在,

当我们的注意力
被当前的大流行所吸引时。

我们每天都在玩溢出
概率游戏

,让我们完整的医疗诊断
开发和监测能力

只专注于当前的大流行
并不会让我们受益。

这次大流行是一个警钟。

虽然很糟糕,

但情况可能会更糟——

第一个
SARS 冠状病毒的致死率要高出 10 倍。

我们正
倾注大量精力和心痛

来应对
COVID-19 的日常威胁。

但我们也必须首先关注

导致其出现
的因素。

保护
不仅仅是保护可爱的动物

和美丽的景色 -

它还涉及保护我们。

COVID-19 发自内心地向我们展示
了可能出现的问题。

现在是
我们真正投资于我们的保护目标、

减少溢出的可能性

并确保我们
在下一次大流行开始之前阻止它的时候了。

谢谢你。