Why do animals have such different lifespans Joao Pedro de Magalhaes

For the microscopic lab worm, C. elegans

life equates to just
a few short weeks on Earth.

Compare that with the tortoise,
which can age to more than 100 years.

Mice and rats reach the end of their lives
after just four years,

while for the bowhead whale,
Earth’s longest-lived mammal,

death can come after 200.

Like most living things,

the vast majority of animals gradually
degenerate after reaching sexual maturity

in the process known as aging.

But what does it really mean to age?

The drivers behind this process are varied
and complicated,

but aging is ultimately
caused by cell death and dysfunction.

When we’re young,
we constantly regenerate cells

in order to replace dead and dying ones.

But as we age, this process slows down.

In addition, older cells don’t perform
their functions as well as young ones.

That makes our bodies go into a decline,

which eventually results
in disease and death.

But if that’s consistently true,

why the huge variance in aging patterns
and lifespan within the animal kingdom?

The answer lies in several factors,

including environment

and body size.

These can place powerful evolutionary
pressures on animals to adapt,

which in turn makes the aging process
different across species.

Consider the cold depths of the Atlantic
and Arctic Seas,

where Greenland sharks can live
to over 400 years,

and the Arctic clam known as the quahog
can live up to 500.

Perhaps the most impressive of these
ocean-dwelling ancients

is the Antarctic glass sponge,

which can survive over 10,000 years
in frigid waters.

In cold environments like these,
heartbeats and metabolic rates slow down.

Researchers theorize that this also
causes a slowing of the aging process.

In this way, the environment
shapes longevity.

When it comes to size,
it’s often, but not always,

the case that larger species have a longer
lifespan than smaller ones.

For instance, an elephant or whale
will live much longer

than a mouse, rat, or vole,

which in turn have years on flies
and worms.

Some small animals, like worms and flies,

are also limited by the mechanics
of their cell division.

They’re mostly made up of cells that can’t
divide and be replaced when damaged,

so their bodies expire more quickly.

And size is a powerful evolutionary driver
in animals.

Smaller creatures are more prone
to predators.

A mouse, for instance, can hardly expect
to survive more than a year in the wild.

So, it has evolved to grow and reproduce
more rapidly,

like an evolutionary defense mechanism
against its shorter lifespan.

Larger animals, by contrast, are better
at fending off predators,

and so they have the luxury of time
to grow to large sizes

and reproduce multiple times
during their lives.

Exceptions to the size rule include bats,
birds, moles, and turtles,

but in each case, these animals have other
adaptations

that allow them to escape predators.

But there are still cases where animals
with similar defining features,

like size and habitat,

age at completely different rates.

In these cases, genetic differences,

like how each organism’s cells
respond to threats,

often account for the discrepancies
in longevity.

So it’s the combination
of all these factors

playing out to differing degrees
in different animals

that explains the variability we see
in the animal kingdom.

So what about us?

Humans currently have
an average life expectancy of 71 years,

meaning that we’re not even close to being
the longest living inhabitants on Earth.

But we are very good at increasing
our life expectancy.

In the early 1900s, humans only lived
an average of 50 years.

Since then, we’ve learned to adapt
by managing many of the factors

that cause deaths,

like environmental exposure
and nutrition.

This, and other increases
in life expectancy

make us possibly the only species
on Earth

to take control over our natural fate.

对于微观实验室蠕虫来说,秀丽隐杆线虫的

生命相当于
地球上短短几周的时间。

与乌龟相比,
它的年龄可以超过 100 岁。

老鼠和老鼠在短短四年后就走到了生命的尽头

而对于
地球上寿命最长的哺乳动物弓头鲸来说,

200 岁之后就会死亡。

与大多数生物一样

,绝大多数动物在人类
达到性成熟后逐渐退化

。 过程称为老化。

但衰老的真正含义是什么?

这一过程背后的驱动因素多种多样
且复杂,

但衰老最终
是由细胞死亡和功能障碍引起的。

当我们年轻的时候,
我们不断地再生细胞

以取代死亡和垂死的细胞。

但随着年龄的增长,这个过程会减慢。

此外,老细胞
的功能不如年轻细胞。

这使我们的身体衰退

,最终
导致疾病和死亡。

但如果这一直是真的,

为什么
动物王国的衰老模式和寿命存在巨大差异?

答案在于几个因素,

包括环境

和体型。

这些会给动物带来强大的进化
压力以适应,

这反过来又使不同物种的衰老过程
不同。

想想大西洋和北冰洋的寒冷深处

,格陵兰鲨鱼可以活
到 400 岁以上,

而被称为 quahog 的北极蛤
可以活到 500 岁。

也许这些居住在海洋的古人中最令人印象深刻的

是南极玻璃海绵 ,

它可以
在寒冷的水域中存活超过 10,000 年。

在这样的寒冷环境中,
心跳和新陈代谢速度会减慢。

研究人员推测,这也会
导致衰老过程减缓。

通过这种方式,环境
塑造了长寿。

谈到大小
,通常但并非

总是如此,较大的物种比较小的物种具有更长的
寿命。

例如,大象或鲸鱼
的寿命会

比老鼠、老鼠或田鼠长得多,而老鼠或田鼠

的寿命又长于苍蝇
和蠕虫。

一些小动物,如蠕虫和苍蝇,


受到细胞分裂机制的限制。

它们主要由无法
分裂并在受损时被替换的细胞组成,

因此它们的身体会更快地死亡。

体型是动物强大的进化驱动力

较小的生物更容易
受到捕食者的攻击。

例如,一只老鼠几乎不能指望
在野外生存超过一年。

因此,它已经进化为更快地生长和繁殖

就像针对其较短寿命的进化防御机制一样

相比之下,较大的动物更
擅长抵御捕食者

,因此它们有足够的
时间长到大尺寸


在其一生中多次繁殖。

大小规则的例外包括蝙蝠、
鸟类、鼹鼠和海龟,

但在每种情况下,这些动物都有其他
适应能力

,使它们能够逃脱捕食者。

但仍有一些动物
具有相似的定义特征,

如大小和栖息地,

以完全不同的速度老化。

在这些情况下,遗传差异,

例如每个生物体的细胞如何
应对威胁,

通常会导致寿命的差异

因此,
正是所有这些因素

在不同动物中不同程度地发挥作用的组合

,解释了我们
在动物王国中看到的变异性。

那么我们呢?

人类目前
的平均预期寿命为 71 岁,

这意味着我们甚至还没有接近成为
地球上寿命最长的居民。

但是我们非常擅长增加
我们的预期寿命。

在 1900 年代初期,人类
的平均寿命只有 50 年。

从那时起,我们学会了
通过管理许多导致死亡的因素

来适应,

比如环境暴露
和营养。

这一点,以及其他
预期寿命的增加,

使我们可能成为
地球

上唯一能够控制我们自然命运的物种。