How rethinking biology can positively change your life

[Applause]

walking into a classroom at the start of

a new semester

my first priority is to always foster

community and a sense of connection with

my students

to that end i often ask what they’re

excited or nervous about for that

semester

when i was teaching non-majors general

introductory biology

my students often said things like this

to me at the start of the semester

science makes me nervous

i’m not any good at biology science

it’s just not interesting it wasn’t just

my students either

research suggests that non-science

majors struggle to engage with biology

see the relevance to their own lives and

have little motivation to engage with

science outside of the classroom

and it isn’t just university students

either

the general public mistrusts scientists

scientific information

and struggles to see how we go from

scientific questions

to science knowledge maybe you’re

looking at some of these quotes

and you feel the same way science makes

you nervous

you don’t feel like you’re any good at

it or it’s just not interesting to you

but what if i told you that you engage

with biology everywhere

every day that biology is all around us

and more interesting

exciting and accessible than you may

think

acknowledging biology all around us is

important not only because it enriches

our lives

but because confidently engaging with

biology is important for the health

and welfare of society biology is

everywhere

there’s a certain danger associated with

thinking that it’s not

we saw this come to the forefront with

the covid19 pandemic

everyone was forced to engage with

biology and make biologically minded

decisions

some of which were major decisions like

deciding to

homeschool children delaying starting

school by a year

or changing business models we all had

to make decisions about mask wearing

what kinds of masks we would wear what

kind of activities we would pursue how

far we would venture outside of the

house

if at all it isn’t just the covid19

pandemic either

it’s issues ranging from genetic

technologies to vaccines

to climate change biology is in every

aspect of our lives

so let’s take a look at some of the

places where you might see biology

as part of your life because when we

begin to make these connections

it’s easier to engage with the bigger

issues

i have a three-year-old son he is the

light of my life

and the nice thing about spending time

with a three-year-old is that they’re

not afraid to ask biology questions

one day we’re at the playground and he

handed this to me

it’s smooth it’s leathery if i shake it

makes a rattling noise these were laying

all over the ground

at the playground

i thought this was a great biology

everywhere a moment so we broke it apart

and we found these inside and i took

this picture and i put it on social

media

and i asked my followers what they

thought these were

their hypotheses ranged from fecal

matter

either from a moose or a rabbit

to burn nuts from the colorado wildfires

to some kind of mummified fruit

the answer is that these are seeds and

they are found in a seed pod

of a honey locust tree and if you drive

through colorado in the winter you can

often see these seed pods hanging in the

trees

so biology is everywhere including

laying on the ground

at the playground we also see biology in

our kitchens too

do you like bacon

do you like your bacon crispy which is

my preference we’re soft and chewy which

is the way my husband likes it

why does bacon change colors and become

crispy when it’s cooked to perfection

it’s because bacon is made of protein

and protein folds in our bodies to do

particular jobs

think of it like making an origami boat

if you have a flat piece of paper and

you put in the water

it doesn’t do anything but fold it into

a boat

and it does it floats when we heat

proteins up

they unfold and when they unfold that’s

when we see these color and texture

changes

incidentally unfolded protein is also

easier to eat

now if there’s bacteria in our bacon

before we cook it

its proteins also unfold when we cook it

and unfolded proteins don’t work

which kills the bacterium so that’s why

cooking our food

prevents us from getting food poisoning

so if i asked you do you like protein

biochemistry instead of

do you like bacon how would your

response have been different

when we think about protein biochemistry

in the context of our kitchens

it’s much more accessible and easier to

understand

okay so there’s biology at the

playground and biology in our kitchens

how about biology in our own backyards i

have a bird feeder in my backyard

and it’s the genesis of several

interesting ecological relationships

ecology is a sub-discipline of biology

concerned with the

interrelatedness among organisms

now there’s a lot of bird species in my

backyard and they all visit my feeder

this is a reflection of high bird

biodiversity in colorado

as well as the presence of migration

routes along the front range of the

rocky mountains

some birds come to my feeder and they

dig around they make a big mess on the

ground

other birds like nut hatches come in and

very carefully pick up a single seed

and fly away with it now the squirrels

they’re also very interested in my bird

feeder as well

but they can’t reach it but they can get

to those seeds on the ground

and so the squirrels and the birds eat

the seeds and they leave the hulls for

me to clean up

or just sweep out into my backyard and

so those hulls in the backyard decompose

and release nutrients into the soil

which helps my grass to grow and if my

grass is growing better there’s more

habitat for insects and if there’s more

habitat for insects there’s more birds

coming into my backyard to eat the

insects

and so on and so on

life is all interconnected and all it

takes to see that

is to look out the window now biology we

can see by looking out the window is all

well and good

but what about the biology that we can’t

see very easily

or when a working knowledge of biology

can help us get through life’s

tough moments one night after dinner

i was watching my son play in the

backyard and i turned to my husband and

said

it’s amazing what you can do with a

single cell

my husband gave a sperm cell and i gave

an egg cell and together we made

a new person and from those original

cells

he grew into the happy and energetic

tiny human we see today

having a child is a fascinating

experience in biology in so many ways

everything from the changes my body went

through while pregnant

to fingers that looked surprisingly like

my own but that are on my son’s hands

we had an interesting adventure in

immunology blood typing and genetics

when my son was born

human blood cells has sugars on the

surface so when you hear about somebody

having type a blood

that means they have a type sugars

someone with b

type blood has b type sugars and

somebody with a b

blood has both they have a and b sugars

now for people who have type o blood

like me we don’t have sugars in our

blood cells

you can think of oh like no no sugars on

our blood cells

now what happens if you get someone

else’s blood in your system that doesn’t

match your blood type

your immune system recognizes those

cells as foreign attacks

and destroys them now i have type o

blood

but my son he has type a blood and when

i was in labor

our blood mixed together and my immune

system attacked

his type a blood ultimate result

he was jaundiced when he was born

jaundiced occurs because of excessive

bilirubin in our systems

and bilirubin is caused by blood cell

breakdown

so he spent much of the first few days

of his life sleeping on a billy bed

to break down the excessive bilirubin

now this was terrifying to my husband

and i as first time parents

but knowledge is power and my biology

everywhere oriented mind started

worrying away

trying to figure out what happened how

it happened

and if it could happen again

if i have type o blood how can i have a

son

who’s type a

blood typing is an example of a genetic

phenomenon called codominance

codominance means that if you have a

gene variant you

express it so somebody who has a b blood

has a gene variant for a and a gene

variant for b

and that’s how they can be a b now for

somebody with type o blood like me

i have two gene variants for o so my

genotype

is oo and so i could only pass an o type

variant on to my son

so this means the fact that my son had a

very adventuresome few days of his life

complete with

lots of blood draws was entirely

my husband’s fault

the only way my son could have type a

blood

is because he must have gotten an a-type

gene variant from

my husband so if we draw up the rest of

this planet square and make some

predictions

we’ll see the chances of my husband and

i having another child

that’s jaundice at birth from

incompatibility is at the minimum

50 percent so having a biology over our

minds that helped us get through a tough

first few days with our we also find

biology in the places we least expect it

like in the band room as schools

consider cutting their arts program in

favor of the sciences it’s important to

remember two things

first that biology tells us

about the powerful experience we have

with the arts

and second that intentional combination

of an artistic

and biological viewpoint has led to many

great

discoveries why do we like music

why do we listen to music while we work

why do we feel extensive connection with

those we make music

with it comes down to biological

processes in

our bodies when you get chills listening

to a beautiful piece

of music it’s because a chemical called

dopamine was released in your brain

that sends a connection we feel with

those we make music with

it isn’t just an emotional connection

it’s a physiological connection as well

and it’s thought to have been essential

for human evolution

and it’s not about science or the

arts either art has been foundational to

biology from the very beginning

the first biologist the naturalist they

didn’t have cameras

they had to be able to quickly and

accurately draw what they were seeing

both to document their findings and

communicate it to other

scientists in fact the intentional

combination of an artistic and a

scientific point of view

was foundational to one of the greatest

discoveries in neuroscience

santiago raymond hall was a spanish

scientist

and the father of neuroscience he came

up with a neuron doctrine or the idea

that the functional unit of our brains

is an individual cell called a neuron

he came up with a neuron doctrine by

repeatedly drawing neural tissue

this is one of his drawings

what is so amazing to me about his work

is that you can still find it included

in modern neuroscience textbooks as

reference material

and also touring the world in art

exhibitions for their beauty

whether it’s music or our families the

critters in our backyard

or bacon we experience biology

everywhere

every day when we see biology all around

us

it’s more exciting accessible and

engaging

why does it matter if people see biology

everywhere

or forever leave memories of biology

class locked in the backs of their

brains

never to be thought of again

there are consequences to not engaging

with biology

to thinking that it is something that

exists outside of our lives

rather than as an integral part of who

we are

biology is everywhere from the simple

things we engage in every day

to the complex issues in society we

begin to gain

confidence by looking at how biology

intersects with our daily lives

so that we can then turn an eye to the

bigger issues

the covid19 pandemic forced us to engage

with biology

how the illegal trade of wild animal

meat or bush meat from africa is a major

public health threat

and a conservation crisis to the

reintroduction of endangered species

back to their native lands

particularly species that are apex

predators like the grey wolves

back into lands that are now inhabited

by humans

questions about genetic technology such

as the patentability of genes

a question that raised eyes of imposed

the united states supreme court

in 2012 to what biological research can

tell us about the realities of climate

change

and why seemingly simple consumer

decisions like deciding to reuse

everything from diapers

to straws to grocery bags matter is part

of an ecological

system engaging with biology isn’t just

about knowing these things

it’s about the health and welfare of

society

when we see biology everywhere we engage

and when we engage we realize that we

are

smart enough to understand

that it is interesting

that engaging with biology is about

knowing every little thing

but being okay with engaging with it as

it intersects with our own

lives biology is everywhere

and yes you too can engage with it

you did just now by listening to my talk

so where will you experience biology

next

[掌声] 新学期开始时走进教室,

我的首要任务是始终培养

社区和与学生的联系感

,为此我经常问他们在

那个学期感到兴奋或紧张的

是什么 教非专业的普通

入门生物学

我的学生

在学期开始时经常对我

说这样的话 非科学

专业的学生很难与生物学

打交道,他们看到了与自己生活的相关性,并且

没有动力

在课堂外从事科学工作

,不仅是

大学生,公众也不信任科学家的

科学信息,

并努力了解我们如何 从

科学问题

到科学知识也许你正在

看这些引文

,你会觉得科学让

你紧张 不觉得你很擅长

,或者只是对你不感兴趣,

但如果我告诉你,你

每天都在与生物学打交道,生物学就在我们

身边,比你想象的更有趣、更

令人兴奋和更

容易接受 我们周围的生物学很

重要,不仅因为它丰富

了我们的生活,

而且因为自信地接触

生物学对社会的健康和福利很重要,

生物学

无处不在,

存在一定的危险

,因为

我们认为这不是我们看到

的。 covid19 大流行

每个人都被迫接触

生物学并做出具有生物学意识的

决定

,其中一些是重大决定,例如

决定让

孩子在家

上学,推迟一年上学

或改变商业模式

穿什么

样的活动,我们会追求什么样的活动

,如果有的话,我们会在屋外冒险多远

不仅仅是covid19

大流行

,从基因

技术到疫苗

再到气候变化生物学的问题都存在于

我们生活的方方面面,

所以让我们来看看

您可能将生物学

视为生活一部分的一些地方,因为当我们

开始建立这些联系

更容易处理更大的

问题

我有一个三岁的儿子 他

是我生命中的光

一个三岁的孩子共度时光的好处是他们

不害怕

有一天我们在操场上问生物问题,他

把这个递给我,

它很光滑,它很坚韧,如果我摇晃它

会发出嘎嘎的声音,这些东西在

操场的地上

铺满了

我认为这是一个很棒的生物。

所以我们把它拆开

,我们在里面找到了这些,我拍了

这张照片,我把它放在社交

媒体上

,我问我的追随者他们

认为这些是

他们的假设

,从驼鹿或兔子的粪便

将科罗拉多州野火中的坚果烧成

某种木乃伊

答案是这些是种子,

它们存在于刺槐树的种子荚

中,如果您

在冬天开车经过科罗拉多州,您

经常会看到这些种子荚悬挂 在

树上,

所以生物学无处不在,包括

在操场上躺在地上 我们在厨房里也看到生物学

你喜欢培根

吗 你喜欢培根脆吗 这是

我的偏好 我们又软又耐嚼 这

是我丈夫喜欢的方式

为什么培根

煮熟后会变色并变脆,

这是因为培根是由蛋白质制成的,

而蛋白质在我们体内会折叠以完成

特定的工作

如果你有一张扁平的纸,

你可以把它想象成折纸船 在水中

它什么也不做,只是把它折叠成

一条船

,当我们加热蛋白质时它会漂浮

如果在我们烹饪培根之前,如果我们的培根中有细菌,那么未折叠的蛋白质现在也更容易食用

它的蛋白质在我们烹饪时也会展开,

并且未折叠的蛋白质不起作用

,这会杀死细菌,所以这就是为什么

烹饪我们的食物

可以防止我们食物中毒

所以如果我问你你喜欢蛋白质

生物化学而

不是你喜欢培根,当我们在厨房的背景下考虑蛋白质生物化学时,你的

反应会有什么不同?

它更容易理解也更容易

理解 和我们厨房里的

生物学 我们自己的后院里的生物学怎么样 我的后

院里有一个喂鸟器

,这是几种

有趣的生态关系的起源

在我的

后院,他们都参观了我的喂食器,

这反映了

科罗拉多州

以及

沿着落基山脉的前线存在迁徙路线

一些鸟类来到我的喂食器并

四处挖掘它们在地面上弄得一团糟

其他鸟类像坚果孵化器一样进来并

非常小心地捡起一颗种子

并带着它飞走 现在松鼠

们也对我的喂鸟器很感兴趣,

但是他们够不到,但他们可以

拿到地上的种子

,所以松鼠和鸟儿吃掉

了种子,他们把外壳留给

我 清理

或只是扫到我的后院,

所以后院的那些船体分解

并将营养物质释放到土壤中

,这有助于我的草生长,如果我的

草长得更好

,昆虫的栖息地就会更多,如果昆虫的栖息地更多

,那么昆虫的栖息地就会更多 鸟儿

进入我的后院吃

昆虫

等等生活都是相互联系的,只要

看看窗外,现在我们

可以通过窗外看到生物学一切都

很好 很好,

但是对于我们不太容易看到的生物学,

或者当生物学的实用知识

可以帮助我们度过生活中的

艰难时刻时,晚饭后的一天晚上

我看着我儿子在

后院玩耍,我转向我丈夫

你可以用一个细胞做什么真是太神奇了

我丈夫给了一个精子细胞,我给了

一个卵细胞,我们一起创造

了一个新人,他从那些原始

细胞

成长为我们今天看到的快乐而充满活力的

小人,

有一个孩子 从

很多方面来说,这是一次引人入胜的生物学体验,

从怀孕期间我的身体经历的变化

到看起来像

我自己的手指,但那是在我儿子的手上

当我儿子出生时,我们在免疫学血型和遗传学方面进行了一次有趣的冒险 出生的

人类血细胞表面有糖,

所以当你听说有人

有 a 型血时

,这意味着他们有 a 型糖

有 b

型血的人有 b 型糖和

someb ab

血的 ody 现在有 a 和 b 糖,

对于像我这样的 o 型血的人来说

,我们的

血细胞中

没有糖,你可以想像

我们的血细胞

现在没有糖,如果你会发生什么

在您的系统中获取

与您的血型不匹配的其他人的血液

您的免疫系统将这些

细胞识别为外来攻击

并破坏它们现在我有o型

但我儿子他有a型血当

我在分娩时

我们的血液混合 一起,我的免疫

系统攻击

了他的血型 最终结果

他出生时有

黄疸 黄疸的发生是因为

我们的系统中胆红素过多,

而胆红素是由血细胞分解引起的,

所以他生命的前几天大部分时间都在

睡觉 一张比利床

来分解过多的胆红素

现在这对我丈夫

和我作为第一次做父母的我来说是可怕的,

但知识就是力量,我的生物学

无处不在,我开始

担心

试图弄清楚你 t 发生了

什么 它是如何发生的

如果我有 o 型血,我怎么可能有一个

儿子是 o 型

血型是称为共性的遗传现象的一个例子

共性意味着如果你有一个

基因变异,你会

表达它 所以有 ab 血的人

有 a 的基因变异和 b 的基因

变异

,这就是现在对于

像我这样的 o 型血的人来说,他们可以是 ab

我有两个 o 的基因变异,所以我的

基因型

是 oo,所以我可以 只将 o 型

变种传给我儿子,

所以这意味着我儿子一生中经历了

非常冒险的几天,

抽了很多血,这完全是

我丈夫的错

,我儿子可能有 A 型血的唯一方法

是因为 他一定是从我丈夫那里得到了一个 a 型

基因变异

所以如果我们绘制这个星球的其余部分

并做出一些

预测,

我们会看到我丈夫和

我有另一个

出生时因 abo 不相容而患有黄疸的孩子的机会

是 至少有

50%,所以在我们的脑海里有一个生物学,

这帮助我们度过了艰难的

最初几天

科学 重要的是要

记住两件事,

第一,生物学告诉

我们我们在艺术方面的强大经验

,第二,

艺术

和生物学观点的有意结合导致了许多

伟大的

发现 为什么我们喜欢音乐

为什么我们听音乐 当我们工作时,

为什么我们会觉得

与我们制作音乐的人

有广泛的联系?这归结为

我们身体的生物过程,当你听到美妙的音乐时会发冷

,那是因为

你的大脑中释放了一种叫做多巴胺的化学物质

,它发出了一种联系 我们觉得

与我们一起创作音乐的人

不仅是一种情感上的联系,

它也是一种生理上的联系,

并且被认为具有

对人类进化至关重要,

与科学

或艺术无关 艺术

从一开始就是生物学的基础

第一位生物学家 博物学家 他们

没有相机

他们必须能够快速

准确地画出他们所看到

的东西 记录他们的发现并将其

传达给其他

科学家事实上,

艺术和

科学观点的有意结合

是神经科学最伟大发现之一的基础

圣地亚哥雷蒙德霍尔是西班牙

科学家

,他提出了神经科学之父

神经元学说或

认为我们大脑的功能单位

是一个称为神经元的单个细胞的想法

他通过反复绘制神经组织提出了神经元学说

这是他的一幅画

他的作品让我感到惊讶的

是,你 仍然可以

在现代神经科学教科书中找到它作为

参考资料

,也可以在艺术

展览中环游世界 离子因为它们的美丽

无论是音乐还是我们的家人

我们后院的小动物

或培根我们

每天都在到处体验生物学当我们看到我们周围的生物时

它更令人兴奋且

引人入胜

为什么人们到处都能看到生物学

或永远留下记忆 生物

课被锁在他们的

大脑深处,

再也

不会被想到 不

接触生物学会

导致认为它是

存在于我们生活之外的东西,

而不是作为我们是谁的一个组成部分

生物学无处不在 从

我们每天从事的简单事情

到社会中的复杂问题 我们

开始

通过观察生物学如何

与我们的日常生活相交来获得信心,

这样我们就可以将目光转向

更大的

问题 covid19 大流行迫使我们如何

与生物学打交道

来自非洲的野生动物肉或丛林肉的非法贸易是一项重大的

公共卫生威胁

,也是对非洲国家的保护危机

将濒临灭绝的物种

重新引入它们的本土,

特别是

像灰狼这样的顶级掠食者物种

回到现在人类居住的土地

关于基因技术的问题,

例如基因的可专利性

这个问题引起

了美国最高法院的关注

2012 年,生物学研究可以

告诉我们气候变化的现实,

以及为什么看似简单的消费者

决定,比如决定重复使用

从尿布

、吸管到食品袋的所有东西,是

与生物学相关的生态系统的一部分,而不仅仅是

了解这些

这关乎社会的健康和福利

当我们在任何地方看到生物学

时,当我们参与时,我们意识到我们

足够聪明,能够

理解有趣的

是,参与生物学是

了解每一件

小事,但可以接受它 因为

它与我们自己的生活相交,

生物学无处不在

,是的哟 你也可以

通过听我的演讲来参与你刚才所做的

事情,那么接下来你将在哪里体验生物学