What is HPV and how can you protect yourself from it Emma Bryce

At some point,

most sexually active people will be
infected with human papillomavirus,

or ‘HPV.’

There are over 100 types of HPV,

and most of the time the body
eliminates infections without symptoms–

but some strains can pose serious
health risks down the line.

HPV causes contact infections,

which means the virus stays in the cells
near the point of infection

rather than spreading throughout
the whole body.

Since HPV is often transmitted through
sexual activity,

this usually means the cells of the
vagina, vulva, penis, anus,

mouth and throat.

We can test for HPV in cells from
these areas,

but while testing for the virus
is scientifically possible,

it isn’t common.

The main reason is that,

while there are treatments for the
adverse health effects caused by HPV,

there’s no treatment for the virus itself.

So testing for HPV would yield many,
many positives,

and although most of them won’t
be cause for concern,

there is still no treatment plan for
clearing the body of the virus.

But there are other good ways to
protect yourself from HPV.

We’re going to walk through how
HPV can cause harm,

who’s at risk, and how to
minimize those risks.

The body’s immune system is able to
eradicate most strains of HPV

before they cause any harm—

and without people even knowing
they’ve been infected.

Certain other strains–

like HPV 6 and 11–

cause abnormalities in the cells of the
infected tissue,

which can develop into genital warts.

While these are infectious
and require treatment,

usually with topical creams,

wart-causing strains don’t create
longer-term damage.

But another 13 strains can cause DNA
mutations that cause cells to divide

at a much faster pace than normal,

propelling the development of
cancerous growths.

The cells of the cervix are
especially at risks.

Two in particular–

HPV 16 and 18–

are responsible for the majority of
cases of cervical cancer,

which is now the fourth most common
type of cancer in women.

It can take up to 20 years for cancer
symptoms to appear,

but with regular screening,

we can discover cellular abnormalities
in the cervix

before they develop into cancer.

Women over 21 can undergo a regular
pap smear,

where a sample of tissue is gently
scraped from the lining of the cervix

to test for abnormal cells.

A positive test doesn’t mean the person
has cervical cancer,

but rather that there are irregular
cells in the cervix

that could develop into cancer
in the future.

Patients are then either monitored
with more frequent pap smears,

or, for more severe irregularities,

undergo a procedure called a colposcopy.

This involves a doctor examining the
cervix through a microscope,

and possibly taking a small biopsy of
tissue for closer examination.

In some cases, the affected tissue
may be removed.

HPV infections of the throat may lead to
head and neck cancers,

but for now there’s no equivalent of the
pap smear for the throat.

Using condoms helps prevent
the spread of HPV during sex.

And there are three safe, effective
vaccines that all target HPV 16 and 18.

The vaccine comes in two or three doses
a few months apart,

and it’s only beneficial if you
receive them all.

Right now the vaccine is part of standard
care for girls aged 11 to 18

in many countries–

though it’s increasingly becoming
available to boys as well.

Adult women and men in countries including
the United States and the United Kingdom

can opt to receive the vaccine,

and evidence suggests that vaccination of
women and men

could reduce the worldwide incidence of
cervical cancer by almost 90%.

Researchers are also
developing an injection

for people who are already infected
with HPV 16 and 18,

which would target the infected cells

to stop them from developing
into cancerous ones.

So while there’s still room for
improvement in screening,

treatment, and access to each,

condom use, vaccination,
and cervical screening

can each reduce the harm caused by HPV.

在某些时候,

大多数性活跃的人会
感染人乳头瘤病毒

或“

HPV”。HPV 有 100 多种类型

,大多数情况下,人体会在
没有症状的情况下消除感染——

但有些菌株可能会在未来造成严重的
健康风险 线。

HPV 会导致接触性感染,

这意味着病毒会留在
感染点附近的细胞中,

而不是在
整个身体中传播。

由于 HPV 通常通过
性活动传播,

这通常是指
阴道、外阴、阴茎、肛门、

口腔和喉咙的细胞。

我们可以在这些区域的细胞中检测 HPV

但虽然检测病毒
在科学上是可行的,

但并不常见。

主要原因是,

虽然有针对
HPV 引起的不良健康影响

的治疗方法,但没有针对病毒本身的治疗方法。

因此,对 HPV 的检测会产生很多
很多阳性结果

,尽管其中大多数
不会引起关注,

但仍然没有
清除体内病毒的治疗计划。

但还有其他
保护自己免受 HPV 感染的好方法。

我们将介绍 HPV 是
如何造成伤害的,

谁有风险,以及如何
将这些风险降到最低。

人体的免疫系统能够在
大多数 HPV 毒株

造成任何伤害之前根除它们——

而且人们甚至不知道
自己已被感染。

某些其他菌株(

如 HPV 6 和 11)

会导致受感染组织的细胞出现异常

从而发展为生殖器疣。

虽然这些是传染性的
并且需要治疗,

通常使用外用乳膏,但

引起疣的菌株不会造成
长期损害。

但另外 13 种菌株会引起 DNA
突变,导致细胞以

比正常速度更快的速度分裂,

从而促进
癌症生长的发展。

子宫颈细胞
尤其处于危险之中。

特别是两种

——HPV 16 和 18——

是导致大多数
宫颈癌病例的原因,宫颈癌

现在是女性第四大常见
癌症类型。

出现癌症症状可能需要长达 20 年的时间

但通过定期筛查,

我们可以
在宫颈癌

发展为癌症之前发现宫颈细胞异常。

21 岁以上的女性可以定期进行
子宫颈抹片检查,

从子宫颈内膜轻轻刮取组织样本

以检测异常细胞。

阳性测试并不意味着该人
患有宫颈癌,

而是宫颈中有不规则
细胞,将来

可能会发展成
癌症。

然后
通过更频繁的子宫颈抹片检查对患者进行监测,

或者对于更严重的异常情况,

接受称为阴道镜检查的程序。

这涉及医生
通过显微镜检查子宫颈,

并可能对组织进行小活检以
进行更仔细的检查。

在某些情况下,可能会移除受影响的组织

喉咙的 HPV 感染可能会导致
头颈癌,

但目前还没有
与咽喉巴氏涂片相当的方法。

使用避孕套有助于
防止 HPV 在性交过程中传播。

并且有三种安全、有效的
疫苗都针对 HPV 16 和

18。疫苗会间隔几个月接种两到三剂

,只有在您
全部接种时才有益处。

目前,该疫苗已成为许多国家
11 至 18 岁女孩标准护理的一部分——

尽管它也越来越多地
提供给男孩。 美国和英国等

国家的成年女性和男性

可以选择接种疫苗,

有证据表明,
女性和男性接种疫苗

可以将全球宫颈癌发病率
降低近 90%。

研究人员还在

为已经
感染 HPV 16 和 18 的人开发一种注射剂,

该注射剂将针对受感染的

细胞阻止它们发展
为癌变细胞。

因此,尽管
在筛查、

治疗和获取方面仍有改进的空间,但

安全套的使用、疫苗接种
和宫颈筛查

都可以减少 HPV 造成的危害。