The wacky history of cell theory Lauren RoyalWoods

One of the great things about science

is that when scientists make a discovery,

it’s not always in a prescribed manner,

as in, only in a laboratory
under strict settings,

with white lab coats

and all sorts of neat
science gizmos that go, “Beep!”

In reality,

the events and people involved

in some of the major
scientific discoveries

are as weird and varied as they get.

My case in point:

The Weird History of the Cell Theory.

There are three parts to the cell theory.

One: all organisms are composed
of one or more cells.

Two: the cell is the basic
unit of structure

and organization in organisms.

And three: all cells come
from preexisting cells.

To be honest, this all sounds
incredibly boring

until you dig a little deeper

into how the world
of microscopic organisms,

and this theory came to be.

It all started in the early 1600s
in the Netherlands,

where a spectacle maker
named Zacharias Janssen

is said to have come up
with the first compound microscope,

along with the first telescope.

Both claims are often disputed,

as apparently he wasn’t the only bored guy

with a ton of glass lenses
to play with at the time.

Despite this,

the microscope soon became a hot item

that every naturalist or scientist
at the time wanted to play with,

making it much like the iPad of its day.

One such person

was a fellow Dutchman by the name
of Anton van Leeuwenhoek,

who heard about
these microscope doohickeys,

and instead of going out and buying one,

he decided to make his own.

And it was a strange
little contraption indeed,

as it looked more like a tiny paddle
the size of a sunglass lens.

If he had stuck two together,

it probably would have made
a wicked set of sunglasses

that you couldn’t see much out of.

Anyhoo, once Leeuwenhoek
had his microscope ready,

he went to town,

looking at anything and everything
he could with them,

including the gunk on his teeth.

Yes, you heard right.

He actually discovered bacteria

by looking at dental scrapings,

which, when you keep in mind

that people didn’t brush their teeth
much – if at all – back then,

he must have had a lovely bunch
of bacteria to look at.

When he wrote about his discovery,

he didn’t call them bacteria,
as we know them today.

But he called them “animalcules,”

because they looked
like little animals to him.

While Leeuwenhoek was staring
at his teeth gunk,

he was also sending letters
to a scientific colleague in England,

by the name of Robert Hooke.

Hooke was a guy who really loved
all aspects of science,

so he dabbled in a little bit
of everything, including physics,

chemistry and biology.

Thus it is Hooke who we can thank
for the term “the cell,”

as he was looking at a piece of cork
under his microscope,

and the little chambers he saw
reminded him of cells,

or the rooms monks slept in
in their monasteries.

Think college dorm rooms,

but without the TVs, computers
and really annoying roommates.

Hooke was something
of an underappreciated scientist

of his day –

something he brought upon himself,

as he made the mistake of locking horns

with one of the most famous
scientists ever, Sir Isaac Newton.

Remember when I said Hooke
dabbled in many different fields?

Well, after Newton published
a groundbreaking book

on how planets move due to gravity,

Hooke made the claim

that Newton had been inspired
by Hooke’s work in physics.

Newton, to say the least,
did not like that,

which sparked a tense
relationship between the two

that lasted even after Hooke died,

as quite a bit of Hooke’s research –
as well as his only portrait –

was … misplaced, due to Newton.

Much of it was rediscovered,
thankfully, after Newton’s time,

but not his portrait,

as, sadly, no one knows
what Robert Hooke looked like.

Fast-forward to the 1800s,

where two German scientists
discovered something

that today we might find rather obvious,

but helped tie together
what we now know as the cell theory.

The first scientist
was Matthias Schleiden,

a botanist who liked to study
plants under a microscope.

From his years of studying
different plant species,

it finally dawned on him

that every single plant he had looked at

were all made of cells.

At the same time,

on the other end of Germany
was Theodor Schwann,

a scientist who not only
studied slides of animal cells

under the microscope

and got a special type
of nerve cell named after him,

but also invented rebreathers
for firefighters,

and had a kickin' pair of sideburns.

After studying animal cells for a while,

he, too, came to the conclusion

that all animals were made of cells.

Immediately, he reached out
via snail mail,

as Twitter had yet to be invented,

to other scientists working
in the same field with Schleiden,

who got back to him,

and the two started working
on the beginnings of the cell theory.

A bone of contention arose between them.

As for the last part of the cell theory –

that cells come from preexisting cells –

Schleiden didn’t exactly
subscribe to that thought,

as he swore cells came
from free-cell formation,

where they just kind of spontaneously
crystallized into existence.

That’s when another scientist
named Rudolph Virchow,

stepped in with research showing
that cells did come from other cells,

research that was actually –
hmm … How to put it? –

“borrowed without permission”

from a Jewish scientist
by the name of Robert Remak,

which led to two more feuding scientists.

Thus, from teeth gunk
to torquing off Newton,

crystallization to Schwann cells,

the cell theory came to be
an important part of biology today.

Some things we know
about science today may seem boring,

but how we came to know them
is incredibly fascinating.

So if something bores you,

dig deeper.

It’s probably got a really weird
story behind it somewhere.

科学的一大优点

是,当科学家们发现时

,并不总是以规定的方式进行,

例如,只有在严格设置的实验室里

穿着白色的实验室外套

和各种整洁的
科学小玩意儿,“哔 !”

在现实中,

一些重大
科学发现

所涉及的事件和人物都是千奇百怪的。

我的例子:

细胞理论的奇怪历史。

细胞理论分为三个部分。

一:所有生物都是
由一个或多个细胞组成的。

二:细胞是

生物体结构和组织的基本单位。

第三:所有细胞都
来自预先存在的细胞。

老实说,这一切听起来都
非常无聊,

直到你更深入


了解微生物世界

以及这个理论是如何形成的。

这一切都始于 1600 年代初
的荷兰,

据说一位名叫 Zacharias Janssen 的眼镜制造商

与第一台望远镜一起发明了第一台复合显微镜。

这两种说法都经常引起争议,

因为显然他不是当时唯一一个

带着大量玻璃
镜片玩的无聊人。

尽管如此

,显微镜很快就成为了

当时每个博物学家或科学家
都想玩的热门物品,

使它很像当时的 iPad。

其中

一位名叫安
东·范·列文虎克(Anton van Leeuwenhoek)

的荷兰人听说了
这些显微镜小玩意儿,

于是他没有出去买一个,

而是决定自己做一个。

这确实是一个奇怪的
小装置,

因为它看起来更像
一个太阳镜镜片大小的小桨。

如果他把两个粘在一起,

它可能会制成
一副

你看不到太多东西的邪恶太阳镜。

无论如何,一旦列文虎克
准备好显微镜,

他就去镇上,用显微镜观察他能

看到的任何
东西,

包括他牙齿上的粘液。

是的,你没听错。

他实际上是

通过观察牙齿刮屑发现了细菌

,当你

记住人们没有经常刷牙时
——如果真的刷牙的话——

他一定有一堆可爱
的细菌可供观察。

当他写下他的发现时,

他并没有
像我们今天所知的那样称它们为细菌。

但他称它们为“动物”,

因为它们
在他看来就像小动物。

列文虎克在
盯着自己的牙齿粘糊糊的同时,

也在给
英国一位

名叫罗伯特·胡克的科学同事寄信。

胡克是一个真正热爱
科学各个方面的人,

所以他涉足
了一切,包括物理、

化学和生物学。

因此,我们要感谢胡克
的“牢房”一词,

因为他正在显微镜下观察一块软木塞

,他看到的小房间
让他想起了牢房,

或者僧侣们在修道院里睡觉的房间

想想大学宿舍,

但没有电视、电脑
和真正令人讨厌的室友。

胡克在他那个时代
是一个被低估的

科学家 -

他自己带来的东西,

因为他犯了

与有史以来最著名的
科学家之一艾萨克牛顿爵士锁定角的错误。

还记得我说过胡克
涉足许多不同的领域吗?

好吧,在牛顿出版
了一本

关于行星如何因重力而运动的开创性书籍之后,

胡克

声称牛顿受到
了胡克在物理学方面的工作的启发。

至少可以说,牛顿
不喜欢这样,

这引发
了两人之间的紧张关系,这种关系

甚至在胡克死后仍持续,

因为胡克的相当多的研究——
以及他唯一的肖像——

被……放错了地方, 由于牛顿。 谢天谢地,在牛顿时代之后

,其中大部分被重新发现,

但不是他的肖像,

因为可悲的是,没有人
知道罗伯特胡克的样子。

快进到 1800 年代

,两位德国科学家
发现

了今天我们可能会发现相当明显的东西,

但帮助将
我们现在所知的细胞理论联系在一起。

第一位科学家
是喜欢在显微镜下研究植物的植物学家马蒂亚斯·施莱登(Matthias Schleiden)

从他多年研究
不同植物物种的过程中,

他终于明白,

他所看到的每一株植物

都是由细胞组成的。

与此同时,

在德国的另一端
,科学家西奥多·施万(Theodor Schwann)

不仅

在显微镜下研究动物细胞的玻片

,得到一种
以他命名的特殊神经细胞,

还为消防员发明了循环呼吸器

并拥有 踢一副鬓角。

在研究了动物细胞一段时间后,

他也得出

了所有动物都是由细胞构成的结论。 由于 Twitter 尚未发明

,他立即
通过蜗牛邮件联系

了与施莱登在同一领域工作的其他科学家,施莱登

回复了他,两人开始

研究细胞理论的开端。

他们之间产生了争论。

至于细胞理论的最后一部分

——细胞来自先前存在的细胞——

施莱登并不完全
赞同这种想法,

因为他发誓细胞
来自自由细胞形成

,它们只是自发地
结晶形成存在。

就在那时,另一位
名叫 Rudolph Virchow 的科学家

介入了研究,
表明细胞确实来自其他细胞,

研究实际上是——
嗯……怎么说? ——

“未经许可”

从一位
名叫罗伯特·雷马克的犹太科学家那里“借来”,

这导致了另外两个不和的科学家。

因此,从牙齿粘稠
到扭转牛顿,从

结晶到施万细胞

,细胞理论成为
当今生物学的重要组成部分。

我们
今天对科学的了解可能看起来很无聊,

但我们如何了解它们
却令人难以置信。

所以,如果有什么事情让你感到厌烦,那就

深入挖掘。

它背后的某个地方可能有一个非常奇怪的
故事。