The truth about electroconvulsive therapy ECT Helen M. Farrell

In 1982, a young nurse was suffering
from severe, unrelenting depression.

She couldn’t work, socialize,

or even concentrate well enough
to read the newspaper.

One treatment changed everything.

After two courses of electroconvulsive
therapy, or ECT, her symptoms lifted.

She went back to work, then on to graduate
school, where she earned high grades.

At first, she talked openly about
her life changing treatment.

But as she realized many people had an
extremely negative impression of ECT,

she stopped sharing her experience.

ECT carried a deep stigma,

leftover from a history that bears little
resemblance to the modern procedure.

The therapy was first
used in medicine in 1938.

In its early years, doctors administered a
strong electrical current to the brain,

causing a whole-body seizure
during which

patients might bite their tongues
or even break bones.

Modern ECT is very different.

While a patient is under
general anesthesia,

electrodes deliver a series
of mild electrical pulses to the brain.

This causes huge numbers of neurons
to fire in unison:

a brief, controlled seizure.

A muscle relaxant keeps spasms
from spreading to the rest of his body.

The only physical indication of the
electricity flooding the brain

is a twitching foot.

The treatment lasts for about a minute,
and most patients are able

to resume normal activities about an
hour after each session.

ECT is commonly used to treat severe cases
of major depression or bipolar disorder

in patients who haven’t responded
to other therapies,

or who have had adverse
reactions to medication.

Half or more of those who undergo
treatment experience an improvement

in their symptoms.

Most patients treated with ECT have two or
three sessions per week for several weeks.

Some begin to notice an improvement
in their symptoms after just one session,

while others take longer to respond.

Patients often continue less frequent
treatments for several months to a year,

and some need occasional maintenance
sessions for the rest of their lives.

Modern ECT is much safer than
it used to be,

but patients can still
experience side effects.

They may feel achy, fatigued,
or nauseated right after treatment.

Some have trouble remembering what
happened right before a session—

for example, what they had for
dinner the previous evening.

Rarely, they might have trouble
remembering up to weeks and months before.

For most patients, this memory
loss does improve over time.

What’s fascinating is that despite its
proven track record,

we still don’t know exactly why ECT works.

Neurons in the brain communicate via
electrical signals,

which influence our brain chemistry,
contributing to mood and behavior.

The flood of electrical activity sparked
by ECT alters that chemistry.

For example, ECT triggers the release
of certain neurotransmitters,

molecules that help carry signals between
neurons and influence mental health.

ECT also stimulates the flow of hormones
that may help reduce symptoms of depression.

Interestingly, ECT maintenance works
better when paired with medication,

even in patients who were
resistant to medication before.

As we come to a better
understanding of the brain,

we’ll likely be able to make
ECT even more effective.

In 1995, more than a decade after
her first course of ECT,

the nurse decided to publish an
account of her experience.

Because of the stigma surrounding
the treatment,

she worried that doing so
might negatively impact

her personal and professional life,

but she knew ECT could make a difference
for patients when all else failed.

Though misperceptions about ECT persist,

accounts like hers have helped make
doctors and patients alike

aware of the treatment’s
life changing potential.

1982 年,一位年轻的护士
患有严重的、无情的抑郁症。

她无法工作、社交,

甚至无法集中
精力阅读报纸。

一种治疗改变了一切。

经过两个疗程的电
休克疗法(ECT)后,她的症状得到了缓解。

她回去工作,然后进入研究生
院,在那里她获得了高分。

起初,她公开谈论
了她改变生活的治疗方法。

但当她意识到很多人
对 ECT 有极其负面的印象时,

她停止分享她的经历。

ECT 带有深深的烙印,

这是一段与现代程序几乎没有相似之处的历史遗留
下来的。

该疗法
于 1938 年首次用于医学。

在早期,医生
向大脑施加强电流,

导致全身癫痫发作

患者可能会咬到舌头
甚至骨折。

现代 ECT 非常不同。

当患者处于
全身麻醉状态时,

电极会
向大脑传递一系列温和的电脉冲。

这会导致大量神经元同时放电

:短暂的、受控的癫痫发作。

肌肉松弛剂可防止
痉挛蔓延到身体的其他部位。 电流充斥大脑

的唯一物理迹象

是抽搐的脚。

治疗持续约一分钟
,大多数患者在每次治疗后

约一小时即可恢复正常活动

ECT 通常用于治疗

对其他疗法没有反应

或对药物有不良
反应的重度抑郁症或双相情感障碍患者。

接受治疗的人中有一半或更多的人

的症状有所改善。

大多数接受 ECT 治疗的患者每周进行两次或
三次治疗,持续数周。

有些人
在一次疗程后就开始注意到他们的症状有所改善,

而另一些人则需要更长的时间才能做出反应。

患者通常会
在几个月到一年内继续不那么频繁的治疗

,有些人需要
在他们的余生中偶尔进行维护。

现代 ECT 比以前更安全

但患者仍然会
出现副作用。

他们可能会
在治疗后立即感到疼痛、疲劳或恶心。

有些人很难记住会议
前发生的事情——

例如,他们
前一天晚上的晚餐吃了什么。

很少,他们可能难以
记住几周和几个月前的事情。

对于大多数患者来说,这种记忆
丧失确实会随着时间的推移而改善。

令人着迷的是,尽管它有
良好的记录,

但我们仍然不知道 ECT 的确切原因。

大脑中的神经元通过
电信号进行交流,

这会影响我们的大脑化学,从而影响
情绪和行为。 ECT

引发的大量电活动
改变了这种化学反应。

例如,ECT 触发
某些神经递质的释放,这些神经

递质有助于在神经元之间传递信号
并影响心理健康。

ECT 还可以刺激荷尔蒙的流动,
这可能有助于减轻抑郁症的症状。

有趣的是,ECT 维持
在与药物配合使用时效果更好,

即使在
以前对药物有抗药性的患者中也是如此。

随着我们对大脑有了更好的
了解,

我们可能能够使
ECT 更加有效。

1995 年,在
她第一次接受 ECT 课程十多年后,

这位护士决定
发表她的经历。

由于围绕治疗的耻辱

她担心这样做
可能会对

她的个人和职业生活产生负面影响,

但她知道
当一切都失败时,ECT 可以为患者带来改变。

尽管人们对 ECT 的误解依然存在,但

像她这样的描述有助于让
医生和患者都

意识到这种治疗
改变生活的潜力。