A new way to fight infectious diseases and predict outbreaks

[Music]

in 2019

virus jumped from its natural animal

host

into humans and life as we know it’s

changed

and with this change came questions

what happened how did we get here

can we prevent this from occurring again

we do not have all the answers to these

questions

but one thing we do know is that the

emergence of covid19

did not come as a surprise to scientists

that have been working on emerging

infectious diseases

and this will not be the last

so why should we

expect more infectious diseases

well in the last few decades there’s

been an increase in the number of new

diseases

with 60 percent of these diseases being

zoonosis

what is a zoonosis a zoonosis

is a disease that is caused by a

pathogen that can affect both humans

and animals some well-known zoonoses are

diseases like ebola

rabies avian influenza

also known as bird flu

over 70 percent of zoonosis

come from wildlife but why wildlife

well one of the reasons is an increasing

population with an increasing demand for

resources

has meant that humans are now

encroaching into areas

that were previously uninhabited and

coming into contact

with wildlife and the diseases that they

carry

so the world health organization

regularly releases

a list of priority diseases for research

and development

based on their potential to cause a

public health emergency

and all the diseases on this list are

zoonosis

included in the current list among

others

is covet 19 ebola

zika and disease x

this is x is defined as a currently

unknown disease

but with the potential to cause an

international

epidemic and in 2019

this is x was coveted 19

a zoonosis so

why are zoonosis important

they have widespread effects with both

direct and

indirect costs an example of a direct

cost to humans

is ill health and

premature death

pre-covered it was estimated that

annually

2.5 billion cases of disease

and 2.7 million deaths are due to

zoonosis

when we look at indirect costs

we can consider what is happening right

now with covet 19.

economies are in recession global value

chains have been

disrupted there’s in there’s reduced

international demand for goods

on a person or not we have all been

affected by copy 19

in one way or the other with the loss of

a loved one

the inability to see our friends and

relatives

not to mention the psychological impacts

that this pandemic is having

on our children so

what can we do to mitigate

the effects of stenosis and prepare

for disease x we can use

the one health approach

the one health approach integrates human

health

animal health and environmental health

so in terms of zoonotic diseases it

looks at all the factors

that can lead to the emergence of a

disease or that can increase

the threat of a disease

we shall now look at an example of where

the one health approach was used

successfully

in 1997 there was an outbreak of avian

influenza

also known as bird flu in hong kong

and authorities there devised a one

health

approach to the disease that went on to

be used

in other emerging facial disease

outbreaks after that

so basically what they did was to look

at poultry production and marketing

systems

as well as thick and healthy poultry and

wild birds

in order to determine the roots of

exposure to the virus

and then with this knowledge we’re able

then to design

targeted responses to prevent further

transmission of the disease

in humans and poultry

we can look at another example of how

the one health approach can be used

normally before outbreaks of ebola

in humans there are large outbreaks in

wildlife populations

particularly non-human primates like

gorillas and chimpanzees

so what normally happens is that hunters

will come across

the carcasses of these animals that have

died from ebola

and then both of the carcasses are in

the process

get infected and serve as a primary

source of infection

in their communities so in this case the

one health approach

could be in regular surveillance of

these wildlife populations for disease

education of the hunters on the risks of

butchering carcasses of animals that

they have found dead and looking into

alternative

avenues of life livelihood

for these hunters we’ll look at

one last example mosquito bone

infections like

zika rift valley fever or dengue

we could actually use the one health

approach in prediction of future

outbreaks

by using meteorological data like

temperature

and rainfall to determine when the

environment will be more suited

for mosquito populations so we can see

from these examples that

the one health approach is

a multi-sectoral and multi-disciplinary

approach

but one health is not a new concept

it’s been around in various forms since

the 19th century

but to this day many just pay lip

service to it

as a veterinarian working with zoonosis

i see the need

for this holistic integrated approach

that one health

offers and my veterinary faculty has

always been

a champion of one health but outside

veterinary circles it seems like one

health

is an option and not a necessity

so how can we ensure that one health is

integrated into all levels of our health

response

well it starts with you and me

we need to educate each other on

the use of one health to mitigate

effects of stenosis or prevent

zoonosis and we also need to understand

that some activities

even though seemingly unrelated to

health can actually increase

the risk of stenosis for example

wildlife trades

encroachment into previously uninhabited

areas and natural phenomena like

flooding

our local authorities lawmakers and

traditional leaders

all need to be involved in preventing or

mitigating the effects of such

activities

and natural phenomena traditional

leaders

are hard enough because as i mentioned

earlier

over 70 percent of the nurses come from

wildlife

and where do we find this wildlife we

are found

outside the urban settings in the areas

that are governed

by these traditional leaders we also

need to advocate

for one health to be integrated into

national policy

this national policy should dictate an

integration of line ministries

in the response to zoonosis for example

ministry of

livestock and fisheries ministry of

health minister of mines

and so on but there needs to be an

agency

that oversees this whose mandate is to

ensure that all stakeholders

are involved in this one health response

and this agency

should also conduct and support research

into zoonosis for example looking into

potential spillover

in addition this agency should bridge

the gap

between human or animal or environmental

health research

and government policy

so what will happen

the next time we have disease x

the way we prepare for it now would

determine its severity

and we all have a role to play one

health

integrates human health and more health

and environmental health

and used properly it will ensure that

the next time a disease jumps

from its animal host into humans we will

be ready

with the answers thank you

[Music]

you

[音乐

] 2019 年,

病毒从其天然动物

宿主

跳入人类和生命,因为我们知道它已经

发生了变化

,随着这种变化而来的问题

是发生了什么我们是如何到达这里的

,我们可以防止这种情况再次发生,

我们没有这些问题的所有答案

问题,

但我们确实知道的一件事是,对于一直致力于研究新兴传染病的科学家来说

,covid19 的出现

并不令人惊讶,

而且这不会是最后一次,

所以我们为什么要

在过去的几十年里期待更多的传染病

新疾病的数量有所增加,

其中 60% 是

人畜共患病

什么是人畜共患

病 人畜共患病是一种由

可以影响人类

和动物的病原体引起的

疾病

禽流感

也称为禽流感

超过 70% 的人畜共患病

来自野生动物,但为什么野生动物

很好的原因之一是

人口不断增加 由于对

资源

的需求意味着人类现在正在

侵入

以前无人居住的地区,并

与野生动物及其携带的疾病接触,因此

世界卫生组织根据其潜在

的研究和开发定期发布优先疾病清单

导致

突发公共卫生事件,

并且此列表中的所有疾病都是

人畜共患病

包括在当前列表中

19 埃博拉

寨卡和疾病 x

这是 x 被定义为目前

未知的疾病,

但有可能导致

国际

流行病和 2019

这是 x 令人垂涎

19 人畜共患病

为什么人畜共患病很重要

它们具有

直接和

间接成本的广泛影响 人类直接成本的一个例子

是健康不良和

过早死亡

预计

每年有

25 亿例

当我们查看我们可以控制的间接成本时,疾病和 270 万人死亡是由于

人畜共患病 看看现在正在发生的事情

与 covet 19.

经济处于衰退中 全球价值

链已被

打乱,

国际对个人商品的需求是否减少,

我们都

以一种或另一种方式受到第 19 份损失的影响

亲人无法见到我们的朋友和

亲戚

更不用说

这种流行病

对我们孩子的心理影响那么

我们可以做些什么来

减轻狭窄的影响并

为疾病做好准备x我们可以

使用一种健康

方法 一种健康方法将人类

健康

动物健康和环境健康结合起来,

因此就人畜共患病而言,它

着眼于

可能导致

疾病出现或

增加疾病威胁的所有因素,

我们现在将看一个例子

1997 年成功地使用了一种健康方法,当时香港爆发了禽流

感,

也称为禽流感

,当地当局设计了 制定了一种

针对该疾病的一种健康方法,该方法随后

用于其他新出现的面部疾病

暴发,

因此他们所做的基本上是

查看家禽生产和营销

系统

以及粗壮和健康的家禽和

野生鸟类

,以确定 接触病毒的根源

,然后有了这些知识,我们

就能够设计

有针对性的应对措施,以防止

疾病

在人类和

家禽中进一步传播

人类埃博拉病毒

在野生动物种群中大规模爆发,

特别是大猩猩和黑猩猩等非人类灵长类动物

所以通常情况是猎人

会遇到

这些

死于埃博拉病毒的动物的尸体

,然后这两具尸体都

在处理中

被感染并成为其社区的主要

感染源,

因此在这种情况下,

一种健康方法

可以定期监视

这些野生动物种群,以便

对猎人进行疾病教育,了解

屠宰他们发现死亡的动物尸体的风险,

为这些猎人寻找替代

的谋生途径

就像

寨卡裂谷热或登革热一样,

我们实际上可以使用一种健康

方法来预测未来的

爆发

,方法是使用

温度

和降雨等气象数据来确定何时

环境更

适合蚊子种群,因此我们可以

从这些例子

中看到 健康方法是

一种多部门和多学科的

方法,

但一种健康并不是一个新概念,

它自 19 世纪以来就以各种形式出现

但直到今天

作为一名处理人畜共患病的兽医,许多人只是口头上说它,

我看到了 需要

一种健康

提供的这种整体综合方法,而我的兽医学院一直在

是一种健康的拥护者,但在

兽医界之外,似乎一种

健康

是一种选择,而不是必需品,

所以我们如何确保一种健康

融入我们健康应对的各个层面,

从你和我开始,

我们需要 相互教育

如何使用一种健康来

减轻狭窄的影响或预防

人畜共患病,我们还需要了解

,一些

看似与健康无关的活动

实际上会增加

狭窄的风险,例如

野生动物贸易

侵入以前无人居住的

地区和自然 像

淹没

我们的地方当局立法者和

传统领导人这样的现象

都需要参与预防或

减轻此类

活动

和自然现象的影响传统

领导人

已经够难了,因为正如我

之前提到的,

超过 70% 的护士来自

野生动物

,我们在哪里 找到我们

在这些地区的城市环境之外发现的这种野生

动物 在

这些传统领导人的领导下,我们还

需要倡导

将一种健康纳入

国家政策,

这项国家政策应规定

职能部委在应对人畜共患病方面的整合,例如

畜牧和渔业部

卫生部矿业部长

和 依此类推,但需要有一个

机构

对此进行监督,其任务是

确保所有利益相关者

都参与这一卫生应对措施,

并且该机构

还应开展和支持

人畜共患病研究,例如调查

潜在的溢出效应

,此外,该机构应弥合

人类或动物或环境

健康研究

与政府政策之间的差距

那么

下次我们患上疾病时会发生什么

x 我们现在为它做准备的方式将

决定它的严重程度

,我们都可以发挥作用 一个

健康

综合人类健康等等 健康

和环境健康

并正确使用它将

确保下一次 e 一种疾病

从它的动物宿主传播到人类我们

将准备

好答案谢谢

[音乐]