Alicia Chong Rodriguez A smart bra for better heart health TED

I am proudly named Alicia
after my grandma.

She dedicated her life
to women’s health as an obstetrician,

in a time when women were rarely allowed
to obtain medical degrees.

We lost her to a heart attack
when I was 13 years old.

When one of my cofounders, Monica, was 12,

she was waiting at school
for her mom to pick her up.

Only that didn’t happen,

because her mom, a 44-year-old physician,

had suddenly passed away from a stroke.

Unfortunately, our stories are common.

Heart disease and stroke

are the leading causes of death
and disability worldwide.

And for women,

it is not only harder to recognize,
diagnose and treat,

but after a heart attack or a stroke,
women also face higher mortality.

There are about 44 million women
living in the US with heart disease,

and the incidences for women
under 65 are on the rise.

So what’s going on?

The answer lies at the intersection
of two areas: data and medical devices.

Let’s look at data first,

or the lack of it.

When I was doing
cardiovascular research at MIT,

I had access to huge data sets.

Realizing that women were one
of the largest subgroups underrepresented

was eye-opening.

In fact, women were basically excluded
from cardiovascular clinical trials

until the NIH mandated inclusion in 1993.

This is why existing technologies
and therapies often fall short,

because most of them have been designed

using data primarily
from male animals and men.

And as artificial intelligence
helps turbocharge digital health,

there’s a danger that algorithms
mostly trained with male data and biases

will actually perpetuate the problem.

Next, let’s look at medical devices.

The “one type fits all” approach

doesn’t even take into account the fact
that heart disease and stroke

can present differently in women.

Way too often, female thresholds
are not programmed.

Smaller arteries cannot be visualized,

and poor clinical-grade monitoring systems

cannot accommodate
two different body shapes

or stages in life.

In the 1800s, Amelia Bloomer
led a movement against damaging corsets,

towards more comfortable
and useful garments for women.

She inspired us to think:

What if we could solve both the data
and the device challenge

by using a garment
that most women already wear daily?

What if a garment
designed to support women

could also augment their health?

Our idea is to turn the everyday bra
into an actual lifesaver.

And this is how we’re doing it.

This is our augmented garment platform.

It gives women the ability

to continuously and remotely
acquire physiological data.

By wearing these bras,

women can view insights and patterns

and keep an automated
journal in their phones,

giving them a simple way to tag symptoms

and collect life-saving data
to share with their doctors

for early detection
and targeted management.

It can even track the safety
and efficacy of certain therapies.

We’ve built medical-grade textile sensors

that can adapt to multiple
bra styles and sizes

for continuous, reliable
and repeatable data,

all around her torso and her heart.

We can track heart rhythm, breathing,
temperature, posture and movement,

and by applying algorithms,
we can use this data to decode symptoms,

articulate arrhythmia triggers

and generate personalized
digital biomarkers.

Unlike traditional biomarkers, like blood,
that take a snapshot in time,

digital biomarkers work more like a video,

using data collected over time
to explain, influence

and even predict health outcomes.

They have the potential
to enable care immediately.

No more wait time for results.

She has the data available
when she needs it the most.

With medical-grade technology
as easy as wearing a bra,

we could catch up, close the data gap,

enable easier participation
in clinical trials

and bring women’s health care
into the 21st century.

The more women that wear
these augmented bras,

the faster we can create
a truly meaningful and inclusive data set

on women’s health.

Collectively, this data
can enable breakthroughs

in digital diagnostics and therapeutics

to solve some of the biggest
health-care challenges

humanity faces today.

With our unique biological data,

our ability to gather more and more of it

and our ability to learn from it using AI,

the dream of making medicine
without bias and truly personal

can be achieved.

And that, of course, benefits all of us.

Thank you.

(Cheers and applause)

我自豪地以
我祖母的名字命名为艾丽西亚。

作为一名产科医生,她毕生致力于女性的健康

,当时女性很少被
允许获得医学学位。 我 13 岁时,

我们因心脏病发作失去了她

当我的一位联合创始人莫妮卡 12

岁时,她正在学校
等她妈妈来接她。

只是那没有发生,

因为她的妈妈,一位 44 岁的医生,

突然中风去世了。

不幸的是,我们的故事很常见。

心脏病和中风


全世界死亡和残疾的主要原因。

而对于女性来说,

不仅更难识别、
诊断和治疗,

而且在心脏病发作或中风之后,
女性还面临更高的死亡率。 美国

约有 4400 万女性
患有心脏病,65 岁

以下女性的发病率
呈上升趋势。

发生什么了?

答案在于两个领域的交叉点
:数据和医疗设备。

让我们先看看数据,

或者说缺少数据。

当我
在麻省理工学院进行心血管研究时,

我可以访问大量数据集。

意识到女性是
代表性不足的最大亚群之一,这

令人大开眼界。

事实上,

在 1993 年美国国立卫生研究院强制要求纳入之前,女性基本上被排除在心血管临床试验之外。

这就是为什么现有技术
和疗法经常不足的

原因,因为它们中的大多数都是

使用主要
来自雄性动物和男性的数据设计的。

由于人工智能
有助于推动数字健康,

存在一种危险,即
主要使用男性数据和偏见训练的算法

实际上会使问题长期存在。

接下来,我们来看看医疗器械。

“一种适合所有人”的方法

甚至没有考虑
到心脏病和中风

在女性中表现不同的事实。

很多时候,女性的
门槛没有被编程。

较小的动脉无法可视化

,临床级监测系统较差,

无法适应
两种不同的身体形状

或生命阶段。

在 1800 年代,Amelia Bloomer
领导了一场反对破坏性紧身胸衣的运动,

旨在
为女性提供更舒适和有用的服装。

她启发我们思考:

如果我们可以

通过使用
大多数女性每天都穿的衣服来解决数据和设备挑战怎么办?

如果
为支持女性

而设计的服装也可以增强她们的健康呢?

我们的想法是将日常文胸
变成真正的救生员。

这就是我们的做法。

这是我们的增强服装平台。

它使女性

能够持续远程
获取生理数据。

通过佩戴这些胸罩,

女性可以查看见解和模式,


在手机中保存一份自动日记,

为她们提供一种简单的方法来标记症状

并收集挽救生命的数据,
以便与医生分享,

以便及早发现
和有针对性的管理。

它甚至可以跟踪某些疗法的安全性
和有效性。

我们构建了医疗级纺织传感器

,可以适应多种
文胸款式和尺寸,在她的躯干和心脏周围

提供连续、可靠
和可重复的数据

我们可以跟踪心律、呼吸、
温度、姿势和运动,

并通过应用算法,
我们可以使用这些数据来解码症状、

阐明心律失常触发因素

并生成个性化的
数字生物标志物。

与及时拍摄快照的血液等传统生物标志物不同,

数字生物标志物更像视频,

使用随时间收集的数据
来解释、影响

甚至预测健康结果。

他们有可能
立即提供护理。

没有更多的等待结果的时间。

在她最需要的时候,她有可用的数据。

借助
像戴胸罩一样简单的医疗级技术,

我们可以迎头赶上,缩小数据差距,

更轻松地
参与临床试验

,并将女性医疗保健
带入 21 世纪。

穿
这些增强型胸罩的女性越多

,我们就越能更快地创建
一个真正有意义和包容性

的女性健康数据集。

总的来说,这些数据
可以实现

数字诊断和治疗方面的突破,

以解决人类今天面临的一些最大的
医疗保健挑战

凭借我们独特的生物数据,

我们收集越来越多的数据的

能力以及我们使用人工智能从中学习的能力,可以实现

没有偏见和真正个人化的制造药物的梦想

当然,这对我们所有人都有好处。

谢谢你。

(欢呼和掌声)