Isha Datar How we could eat real meat without harming animals TED

Diners in Singapore are eating
chicken nuggets

made from a chicken who was never killed.

How is this possible?

Through the power of what I call
“cellular agriculture.”

For the past decade, I’ve been an advocate
for growing meat in a lab.

To me, this chicken nugget,
this hamburger, this sausage –

all made from cells instead of animals –

aren’t just fast-food products.

They’re our ticket to a new food system.

Here’s how it works.

Rather than raise a whole chicken
with beaks, feathers, sentience,

we grow the meat directly
from muscle cells.

We take a small biopsy
from a living animal,

and then extract the cells of interest.

They’re probably muscle cells,

but they could be fat
or connective tissue as well.

Now, muscle cells in particular,
love to attach onto surfaces.

It helps them grow and elongate
into those long muscle fibers

that we’re so familiar with.

So we might provide
a scaffolding material

for those cells to adhere onto.

And then, of course, we have to feed
the cells something.

So we put them in a liquid medium

that provides all the nutrients
that these cells need to grow and divide:

carbohydrates, amino acids,
growth factors and more.

Lastly, the cells
on the scaffold in the medium

all grow within a bioreactor,

which is kind of like a large
stainless steel tank –

looks a lot like brewing equipment
and can be just as big as well.

And the bioreactor really just provides
that constant stable environment

that those cells need to flourish in –

stable temperature, pressure,
inflows, outflows, etc.

And after those cells get a chance
to proliferate and differentiate,

mature into muscle fibers,

we might harvest the cells and the tissues
and then turn them into a nugget,

a nugget that was boneless and skinless
and all white meat to begin with.

Now, this wouldn’t just be better
for chickens and cows and pigs

and the people who have to farm them
and slaughter them and process their meat.

This could be better for the whole world.

Think of this:

early estimates of cell-cultured
meat’s potential

show that cultured meat would require
99 percent less land,

96 percent less water

and produce 96 percent fewer
greenhouse gas emissions.

Now, those are still speculative
early estimates.

But think about the incredible potential
that this technology holds.

I mean, if this all works, this would be
a new subsistence strategy,

a new tool set for producing food.

It wouldn’t just be
a new product category.

And I think it’s our
once-in-a-lifetime opportunity

to get a second chance at agriculture,

to do things better
and to learn from our mistakes.

What do I mean by mistakes?

After all, this is a food system
that keeps billions of people alive, yes.

But look at what has happened to chickens

in just 50 years.

By simply picking which two chickens
to breed with one another,

chickens went from this on the left,
a bird that’s from 1957,

to this on the right, a broiler.

These chickens are the same age.

Broilers have been optimized so much
for meat production

that they must be slaughtered
at six to eight weeks,

because if they live beyond that,

their legs will not be able
to hold up their bodies.

That is real suffering.

What about farms?

Today, animals are
packed together so closely

that the risk of antibiotic resistance
and epidemic viruses

are at all-time highs.

Did you know that 2018 was the beginning

of the largest farmed
animal pandemic ever?

African swine fever has already killed
an estimated one in four pigs on Earth.

One in four pigs,

that is hundreds of millions
of pigs lost from our food supply.

Animal agriculture is simply
too big to not fail.

What about our changing climate?

Did you know that our global herd
of farmed animals

is one of the biggest drivers
and victims of climate change?

On one hand,

cows alone produce nine percent
of all greenhouse gas emissions.

On the other hand,

climate chaos is seeing
more and more incidences of thousands,

sometimes tens of thousands of cattle

being lost overnight in rogue
storms, floods and fires.

Farming is always going to be
at the mercy of Mother Nature,

but climate change is rewriting
the rules of farming as we speak.

We need another way.

Lastly, our planet.

We dedicate more of this Earth
to feeding cows, pigs and chickens

than we do to anything else.

About a third of this planet, 27 percent,

roughly equivalent to all of North
and South America combined,

is dedicated to raising livestock.

Now, this could all change
with cellular agriculture.

Remember how I said it would
require 99 percent less land

to produce cultured meat versus beef?

Well, think about it: ranching
can’t go vertical, but cell culture can.

And if we can alleviate half,
even a quarter, of this land

and meet the global demand for protein,

well, imagine what we can do
with the rest.

Suddenly, it becomes possible
to choose to do things

like restore the Amazon rainforest,
which we continue to clear-cut for cattle,

or revive other ecosystems that have been
colonized by cows, corn and soy.

Or return stolen lands
to Indigenous peoples,

who can finally reclaim
their ancestral foodways.

The United Nations says that
we will have to restore nature

on land the size of China

if we are to achieve climate resilience.

Cellular agriculture actually
puts this on the table.

Not only could we alleviate
land for restoration,

we can also create the products we know
and love at a fraction of the emissions.

By farming cells, we could actually
proactively envision agriculture

for a climate-changed world.

And it’s not just meat.

Actually, by engineering biology,

we could theoretically grow anything
that might come from plants or animals

from cells instead.

Vanilla doesn’t have to be
rainforest farmed.

Egg whites don’t have to come
with a yolk.

Foie gras can be completely cruelty-free,

and leather and silk don’t
have to come off the back of an animal

or the home of a silkworm.

In fact, we already consume
cellular agriculture products

in our everyday lives,

just in supersmall quantities.

Several vitamins, flavors and enzymes
are already made in cell cultures.

In fact, rennet, which is
the set of enzymes used

to turn milk into curds and whey
for cheese-making,

used to come from the stomach lining
of the fourth stomach of calves,

baby cows.

And in 1990, a cell-cultured
version hit the market.

A version of the key enzyme, chymosin.

And today, only 30-ish years later,

90 percent of rennet
used for cheese-making

came from a bioreactor instead of a calf.

Now, imagine what might happen

if we expand beyond these small-volume,
high-value products like rennet

into commodity-level products like milk.

Well, it’s getting started.

Today, you can buy ice cream –
real dairy ice cream –

that was produced by cellular agriculture.

This is cows milk that never
came from a cow.

It came from a computer.

The gene for whey protein was looked up
in an open-source database, printed

and then inserted into the DNA
of an organism called trichoderma.

Now, just like in brewing,
where we feed sugar to yeast

to brew alcohol in a big
stainless steel fermenter,

we feed sugar to this
modified trichoderma

and out comes whey proteins
that we can put in yogurt,

cream cheese and ice cream.

Now, I have to admit that maybe
this is the easy stuff,

relatively speaking.

I mean, we have been modifying
microorganisms to make proteins for us

for decades now.

And tissue engineering, which is what
would be needed for meat production,

is a lot newer science.

I mean, animal cells are just a lot more
finicky than microbes in cell culture,

and growing a lot of animal cells
and achieving three dimensionality

is just no easy feat.

But we’re getting there.

Back in 2013,

it cost 250,00 euros
to produce this hamburger,

and today, I’ve seen estimates
of cell-cultured meats

cost as low as $50 per pound.

That’s one twenty-seven-thousandth
of what it was less than a decade ago.

And I can really only see the price
of cultured meat coming down,

and I can only see the price of meat
from animals going up.

I mean, think about it –
we’re still in the early days of R and D.

As scientific breakthroughs are made,

like recycling growth medium,
reducing the cost of growth factors

and achieving higher
cell density in vitro,

this curve is still going to go down.

Meanwhile, the price of meat from animals
is already artificially low

due to heavy subsidization.

It does not reflect
the cost to the public health

or to the environment.

And, in a world changed by COVID,
African swine fever

and a changing climate,

the price of meat from animals
can only go up.

In fact, I think that price parity would
be well within reach

if it were an even playing field.

On one hand, we have animal agriculture,

which is so heavily supported by public
funding and government support.

On the other hand, we have
this very promising technology,

which requires very intensive R and D

and needs a lot of infrastructure
and training support

but is left entirely in the hands
of the private sector and market forces.

In fact, I don’t think any
of the wonderful things

I just described about rewilding
the Amazon and so on will happen

if we leave this technology
solely in the hands

of technology and market forces.

There’s a real chance that cellular
agriculture could fail,

and it won’t be because
the science doesn’t add up.

It’ll be because we didn’t think about
what ownership should look like

or IP protection

or governance or policy –

you know, the business side
of mission-driven businesses.

And we’re going to have to be
very careful and thoughtful

about what this technology
needs around it

so we can maximize the positive impact
that it will have on this world.

Look, I’m here today because
animal products are just amazing,

and you would be hard-pressed
to find proteins in the plant world

that can do what animal proteins can do:

long, stretchy cheeses,
creamy custards, fluffy meringues,

the incredibly rich umami flavors
that you can find in meat and seafood …

But despite how amazing
animal proteins are,

they just don’t need to come
from animals anymore.

And yes, we’ve got a long way to go

to realize the potential
of this technology,

and it’s going to take ingenuity both
inside of the lab and outside of it, too.

But think about what we get in return.

We get a chance to usher in
a transformation as big for humanity

as our transformation from hunting
to agriculture some 12,000 years ago.

This could be a new era of abundance
in so many different ways.

I’m personally most selfishly excited
for the food products

that I can’t even fathom today,

because this is really a new tool
for culinary creativity as well.

I mean, we haven’t really seen this

since our ancestors discovered
fermentation a while back.

What I mean by that is,

we could have never looked at a glass
of milk before we fermented foods

and wanted it to be hard
and stinky and moldy.

You know, we could have
never envisioned cheese

or the hundreds of varieties
of cheese that we have today.

Similarly, meat is still defined
by the body of an animal.

We still describe it as cuts of meat.

But if we can grow meat from cells,

suddenly the boundaries for what meat
can be will totally change.

Meat could be thin and translucent.

It could be liquid.

It could be crunchy, it could be bubbly.

Burgers are the baseline and sausages
are just a starting point,

and nuggets are nowhere near
what’s possible with cellular agriculture.

Let’s dream up a bigger, bolder
future of food.

Thank you.

(Applause)

新加坡的食客正在吃

由从未被杀死的鸡制成的鸡块。

这怎么可能?

通过我所说的
“细胞农业”的力量。

在过去的十年里,我一直倡导
在实验室种植肉类。

对我来说,这个鸡块、
这个汉堡包、这个香肠——

都是由细胞而不是动物制成的

——不仅仅是快餐产品。

它们是我们通向新食品系统的门票。

这是它的工作原理。

我们不是
用喙、羽毛和知觉养整只鸡,

而是直接
从肌肉细胞中培育出肉。

我们从活体动物身上进行小活检

然后提取感兴趣的细胞。

它们可能是肌肉细胞,

但也可能是脂肪
或结缔组织。

现在,肌肉细胞尤其
喜欢附着在表面上。

它帮助它们生长并拉长

我们非常熟悉的长肌肉纤维。

所以我们可能会为这些细胞提供
一种支架材料

来粘附。

然后,当然,我们必须
给细胞一些东西。

因此,我们将它们放入液体培养基

中,
提供这些细胞生长和分裂所需的所有营养:

碳水化合物、氨基酸、
生长因子等。

最后,
培养基中支架上的细胞

都在一个生物反应器中生长,这个生物反应

器有点像一个大型
不锈钢罐——

看起来很像酿造设备
,也可以和它一样大。

生物反应器实际上只是提供

了这些细胞需要在其中繁衍生息的恒定稳定环境——

稳定的温度、压力、
流入、流出

等。在这些细胞有
机会增殖和分化、

成熟为肌肉纤维之后,

我们可能会收获 细胞和组织
,然后把它们变成

一块块,一块无骨无皮
的块,一开始全是白肉。

现在,这不仅
对鸡、牛和猪

以及必须耕种
、屠宰和加工肉类的人更好。

这对整个世界来说可能会更好。

想一想:

对细胞培养
肉潜力的早期估计

表明,培养肉需要的
土地减少 99%,

用水量

减少 96%,
温室气体排放量减少 96%。

现在,这些仍然是投机性的
早期估计。

但是想想这项技术所拥有的令人难以置信的潜力

我的意思是,如果这一切奏效,这将是
一种新的生存策略,

一种用于生产食物的新工具。

它不仅仅是
一个新的产品类别。

我认为这是我们
千载难逢的

机会,可以在农业领域获得第二次机会,

将事情做得更好,
并从错误中吸取教训。

我所说的错误是什么意思?

毕竟,这是一个
让数十亿人活着的食物系统,是的。

但是看看鸡

在短短 50 年内发生了什么。

通过简单地挑选哪两只鸡
相互繁殖,

鸡从左边的这只鸡,
一只来自 1957 年的鸟,

到右边的这只鸡,一只肉鸡。

这些鸡的年龄相同。

肉鸡已经针对肉类生产进行了如此多的优化,

以至于它们必须
在六到八周时被屠宰,

因为如果它们活得超过这个时间,

它们的腿
将无法支撑它们的身体。

那是真正的痛苦。

农场呢?

今天,动物
紧密地挤在一起

,抗生素耐药性
和流行病毒

的风险处于历史最高水平。

您是否知道 2018 年是有史以来

最大的养殖
动物大流行的开始?

非洲猪瘟已经
导致地球上四分之一的猪死亡。

四分之一的猪,


数亿头猪从我们的食物供应中损失。

畜牧业规模
太大而不能倒闭。

我们不断变化的气候呢?

您知道我们的全球
养殖动物

群是气候变化的最大驱动因素
和受害者之一吗?

一方面,

仅奶牛就产生
了所有温室气体排放量的 9%。

另一方面,

气候混乱
导致越来越多的事件发生,数千头

甚至数万头牛

在一夜之间因
暴风雨、洪水和火灾而丧生。

农业总是
受大自然母亲的摆布,


正如我们所说,气候变化正在改写农业规则。

我们需要另一种方式。

最后,我们的星球。

我们将地球上更多的精力
用于喂养牛、猪和鸡,而

不是其他任何事情。

地球上大约三分之一的土地,即 27%,

大约相当于北美
和南美的总和

,致力于饲养牲畜。

现在,这一切都可能
随着细胞农业而改变。

还记得我说过

生产人造肉比生产牛肉需要的土地少 99% 吗?

好吧,想一想:牧场
不能垂直,但细胞培养可以。

如果我们能够减轻一半
甚至四分之一的土地面积

并满足全球对蛋白质的需求

,那么想象一下我们可以
用剩下的部分做什么。

突然之间,我们
可以选择做一些事情,

比如恢复
我们继续为牛砍伐的亚马逊热带雨林,

或者恢复其他
被奶牛、玉米和大豆殖民的生态系统。

或者将被盗的土地归还
给原住民,

他们最终可以重新夺回
他们祖先的饮食方式。

联合国表示,

如果我们要实现气候复原力,就必须在中国这么大的陆地上恢复自然。

细胞农业实际上
把它放在了桌面上。

我们不仅可以减少
土地用于恢复,

我们还可以以很少
的排放量创造我们熟悉和喜爱的产品。

通过耕种细胞,我们实际上可以
主动设想

气候变化世界的农业。

这不仅仅是肉。

实际上,通过工程生物学,

理论上我们可以从细胞中培育出任何
可能来自植物或动物的东西

香草不必在
雨林种植。

蛋清不一定要
配蛋黄。

鹅肝酱可以完全不残忍

,皮革和丝绸
不必从动物的背上

或蚕的家中脱落。

事实上,我们已经在日常生活中消费了
细胞农业产品

只是数量非常少。

几种维生素、香料和
酶已经在细胞培养物中制成。

事实上,凝乳
酶是一组

用于将牛奶转化为凝乳和乳清
以制作奶酪的酶,它

曾经来自
小牛第四胃的胃壁,即小牛

1990 年,细胞培养的
版本上市。

关键酶凝乳酶的一个版本。

而今天,仅仅 30 年后,用于奶酪制作的

90% 的凝乳酶

来自生物反应器,而不是小牛。

现在,想象一下,

如果我们从凝乳酶等小批量、
高价值产品扩展

到牛奶等商品级产品,会发生什么。

嗯,它开始了。

今天,你可以买到

由细胞农业生产的冰淇淋——真正的乳制品冰淇淋。

这是从未来自母牛的牛奶

它来自计算机。

在开源数据库中查找乳清蛋白基因
,打印出来

,然后插入到
一种叫做木霉的生物体的 DNA 中。

现在,就像在酿造过程中
,我们将糖喂给酵母

以在一个大型
不锈钢发酵罐中酿造酒精,

我们将糖喂给这种
改良的木霉,

然后生产出乳清蛋白
,我们可以将其放入酸奶、

奶油奶酪和冰淇淋中。

现在,我不得不承认
,相对而言,这也许是一件容易的事

我的意思是,几十年来我们一直在改造
微生物来为我们制造蛋白质

肉类生产所需要的组织工程

是一门较新的科学。

我的意思是,动物细胞
比细胞培养中的微生物要挑剔得多,培养

大量动物细胞
并实现三维

空间并不是一件容易的事。

但我们正在到达那里。

早在 2013 年,

生产这种汉堡包的成本为 250,00 欧元,

而今天,我看到
细胞培养肉的

成本估计低至每磅 50 美元。

这是不到十年前的二万七千分之一。

而且我真的只能看到
养殖肉的价格在下降,

而我只能看到动物肉的价格
在上涨。

我的意思是,想想看——
我们还处于研发的早期阶段。

随着科学突破的取得,

比如循环使用生长培养基、
降低生长因子的成本

和实现更高
的体外细胞密度,

这条曲线仍然是 要下去了。

同时,由于大量补贴,动物肉的价格
已经人为降低

它不反映
公共健康

或环境的成本。

而且,在一个因新冠病毒、
非洲猪瘟

和气候变化而改变的世界中

,动物肉的价格
只会上涨。

事实上,我认为

如果它是一个公平的竞争环境,价格平价将是触手可及的。

一方面,我们有畜牧业,

这得到了公共
资金和政府的大力支持。

另一方面,我们拥有
这项非常有前途的技术,

它需要非常密集的研发

,需要大量的基础设施
和培训支持,

但完全
掌握在私营部门和市场力量的手中。

事实上,如果我们将这项技术完全交由技术和市场力量控制,我认为

我刚才描述的关于重新野
化亚马逊等等的任何美妙的事情都不会发生

细胞
农业很有可能会失败

,这不是
因为科学没有加起来。

这是因为我们没有考虑
所有权应该是什么样子,

或者知识产权保护

、治理或政策——

你知道,
任务驱动型企业的业务方面。

我们必须
非常小心和深思熟虑地

考虑这项技术
需要什么,

这样我们才能最大限度地
发挥它对这个世界的积极影响。

看,我今天来到这里是因为
动物产品真是太棒了

,你很难
在植物世界中找到

可以做动物蛋白可以做的蛋白质:

长而有弹性的奶酪、
奶油蛋羹、蓬松的蛋白酥皮,

令人难以置信的
您可以在肉类和海鲜中找到丰富的鲜味……

但尽管
动物蛋白有

多么神奇,它们不再需要
来自动物。

是的,

要实现
这项技术的潜力,我们

还有很长的路要走,而且
在实验室内外都需要独创性。

但是想想我们得到了什么回报。

我们有机会迎来
一场对人类来说意义重大的转变,

就像我们
在大约 12,000 年前从狩猎到农业的转变一样。

这可能是一个
以许多不同方式丰富的新时代。

我个人

今天甚至无法理解的食品感到最自私的兴奋,

因为这
也是烹饪创意的新工具。

我的意思是,

自从我们的祖先不久前发现
发酵以来,我们还没有真正看到过这种情况。

我的意思是,

在我们发酵食物之前,我们不可能看过一杯牛奶,

并希望它变硬
、发臭和发霉。

你知道,我们
从来没有想过奶酪


我们今天拥有的数百种奶酪。

同样,肉仍然是
由动物的身体定义的。

我们仍然将其描述为肉块。

但是,如果我们可以从细胞中培育出肉,

那么肉的界限
就会完全改变。

肉可以是薄而半透明的。

它可能是液体。

它可能是脆的,它可能是起泡的。

汉堡是基线,香肠
只是一个起点,

而金块
远不及细胞农业所能实现的。

让我们梦想一个更大、更大胆
的食品未来。

谢谢你。

(掌声)