Smelfies and other experiments in synthetic biology Ani Liu

What if our plants

could sense the toxicity
levels in the soil

and express that toxicity
through the color of its leaves?

What if those plants could also
remove those toxins from the soil?

Instead, what if those plants

grew their own packaging,

or were designed to only be harvested

by their owners' own patented machines?

What happens when biological design

is driven by the motivations
of mass-produced commodities?

What kind of world would that be?

My name is Ani, and I’m a designer
and researcher at MIT Media Lab,

where I’m part of a relatively new
and unique group called Design Fiction,

where we’re wedged somewhere
between science fiction and science fact.

And at MIT, I am lucky enough
to rub shoulders with scientists

studying all kinds of cutting edge fields

like synthetic neurobiology,

artificial intelligence, artificial life

and everything in between.

And across campus,
there’s truly brilliant scientists

asking questions like,
“How can I make the world a better place?”

And part of what my group
likes to ask is, “What is better?”

What is better for you, for me,

for a white woman, a gay man,

a veteran, a child with a prosthetic?

Technology is never neutral.

It frames a reality

and reflects a context.

Can you imagine what it would say
about the work-life balance at your office

if these were standard issue
on the first day?

(Laughter)

I believe it’s the role
of artists and designers

to raise critical questions.

Art is how you can see
and feel the future,

and today is an exciting
time to be a designer,

for all the new tools becoming accessible.

For instance, synthetic biology

seeks to write biology
as a design problem.

And through these developments,

my lab asks, what are the roles
and responsibilities

of an artist, designer,
scientist or businessman?

What are the implications

of synthetic biology, genetic engineering,

and how are they shaping our notions
of what it means to be a human?

What are the implications of this
on society, on evolution

and what are the stakes in this game?

My own speculative design research
at the current moment

plays with synthetic biology,

but for more emotionally driven output.

I’m obsessed with olfaction
as a design space,

and this project started with this idea

of what if you could take
a smell selfie, a smelfie?

(Laughter)

What if you could take
your own natural body odor

and send it to a lover?

Funny enough, I found that this
was a 19th century Austrian tradition,

where couples in courtship
would keep a slice of apple

crammed under their armpit during dances,

and at the end of the evening,

the girl would give the guy
she most fancied her used fruit,

and if the feeling was mutual,

he would wolf down that stinky apple.

(Laughter)

Famously, Napoleon wrote
many love letters to Josephine,

but perhaps amongst the most memorable
is this brief and urgent note:

“Home in three days. Don’t bathe.”

(Laughter)

Both Napoleon and Josephine
adored violets.

Josephine wore violet-scented perfume,

carried violets on their wedding day,

and Napoleon sent her a bouquet of violets

every year on their anniversary.

When Josephine passed away,

he planted violets at her grave,

and just before his exile,

he went back to that tomb site,

picked some of those flowers,
entombed them in a locket

and wore them until the day he died.

And I found this so moving,

I thought, could I engineer that violet
to smell just like Josephine?

What if, for the rest of eternity,

when you went to visit her site,

you could smell Josephine
just as Napoleon loved her?

Could we engineer new ways of mourning,

new rituals for remembering?

After all, we’ve engineered
transgenic crops

to be maximized for profit,

crops that stand up to transport,

crops that have a long shelf life,

crops that taste sugary sweet
but resist pests,

sometimes at the expense
of nutritional value.

Can we harness these same technologies
for an emotionally sensitive output?

So currently in my lab,

I’m researching questions like,
what makes a human smell like a human?

And it turns out it’s fairly complicated.

Factors such as your diet,
your medications, your lifestyle

all factor into the way you smell.

And I found that our sweat
is mostly odorless,

but it’s our bacteria and microbiome

that’s responsible for your smells,
your mood, your identity

and so much beyond.

And there’s all kinds
of molecules that you emit

but which we only perceive subconsciously.

So I’ve been cataloging and collecting

bacteria from different sites of my body.

After talking to a scientist, we thought,

maybe the perfect concoction of Ani

is like 10 percent collarbone,
30 percent underarm,

40 percent bikini line and so forth,

and occasionally
I let researchers from other labs

take a sniff of my samples.

And it’s been interesting to hear
how smell of the body

is perceived outside
of the context of the body.

I’ve gotten feedback such as,

smells like flowers, like chicken,

like cornflakes,

like beef carnitas.

(Laughter)

At the same time, I cultivate
a set of carnivorous plants

for their ability to emit
fleshlike odors to attract prey,

in an attempt to kind of create
this symbiotic relationship

between my bacteria and this organism.

And as it so happens,
I’m at MIT and I’m in a bar,

and I was talking to a scientist

who happens to be a chemist
and a plant scientist,

and I was telling him about my project,

and he was like, “Well, this sounds
like botany for lonely women.”

(Laughter)

Unperturbed, I said, “OK.”

I challenged him.

“Can we engineer a plant
that can love me back?”

And for some reason,
he was like, “Sure, why not?”

So we started with,
can we get a plant to grow towards me

like I was the sun?

And so we’re looking at mechanisms
in plants such as phototropism,

which causes the plant
to grow towards the sun

by producing hormones like auxin,

which causes cell elongation
on the shady side.

And right now I’m creating
a set of lipsticks

that are infused with these chemicals

that allow me to interact with a plant
on its own chemical signatures –

lipsticks that cause plants
to grow where I kiss it,

plants that blossom
where I kiss the bloom.

And through these projects,

I’m asking questions like,

how do we define nature?

How do we define nature
when we can reengineer its properties,

and when should we do it?

Should we do it for profit, for utility?

Can we do it for emotional ends?

Can biotechnology be used
to create work as moving as music?

What are the thresholds between science

and its ability to shape
our emotional landscape?

It’s a famous design mantra
that form follows function.

Well, now, wedged somewhere
between science, design and art

I get to ask,

what if fiction informs fact?

What kind of R&D lab would that look like

and what kind of questions
would we ask together?

We often look to technology as the answer,

but as an artist and designer,

I like to ask, but what is the question?

Thank you.

(Applause)

如果我们的植物

能够感知
土壤中的毒性水平


通过其叶子的颜色来表达这种毒性呢?

如果这些植物也
能从土壤中去除这些毒素呢?

相反,如果这些植物

自己种植包装,

或者被设计成只能

由其所有者自己的专利机器收获呢?

当生物设计


大批量生产商品的动机驱动时会发生什么?

那会是一个怎样的世界?

我的名字是 Ani,我是
麻省理工学院媒体实验室的设计师和研究员,

在那里我是一个名为 Design Fiction 的相对较新
且独特的小组的一员

,我们被夹
在科幻小说和科学事实之间的某个地方。

在麻省理工学院,我有幸

研究

合成神经生物学、

人工智能、人工生命

等各种前沿领域的科学家并肩作战。

在整个校园里,
有真正杰出的科学家

提出诸如
“我怎样才能让世界变得更美好?”之类的问题。

我的团队
喜欢问的部分问题是,“什么更好?”

对你,对我,

对一个白人女性,一个男同性恋者,

一个退伍军人,一个带着假肢的孩子来说,有什么更好的呢?

技术从来都不是中立的。

它构筑了一个现实

并反映了一个背景。 如果这些都是第一天的标准问题,

你能想象
你办公室的工作与生活平衡会怎么说

吗?

(笑声)

我相信
艺术家和设计师

的职责是提出批判性问题。

艺术是你如何看待
和感受未来的方式

,今天是成为设计师的激动人心的
时刻,

因为所有新工具都变得易于使用。

例如,合成生物学

试图将生物学
写成一个设计问题。

通过这些发展,

我的实验室问,

艺术家、设计师、
科学家或商人的角色和责任是什么?

合成生物学、基因工程的意义是什么

,它们如何塑造我们
对人类意义的观念?


对社会、

进化有何影响?这场博弈的利害关系是什么?

目前我自己的推测性设计研究

与合成生物学有关,

但更多的是情感驱动的输出。

我痴迷于将嗅觉
作为一个设计空间,

而这个项目的开始是这样一种

想法:如果你可以拍
一张气味自拍,一个 smelfie?

(笑声)

如果你能把
自己的自然

体味送给爱人呢?

有趣的是,我发现这
是 19 世纪奥地利的传统,

恋爱中的情侣

在跳舞时会在腋下塞一片苹果

,晚上结束时

,女孩
会给她最喜欢的男人用 水果

,如果这种感觉是相互的,

他会狼吞虎咽地吃掉那个臭苹果。

(笑声)

众所周知,拿破仑
给约瑟芬写了很多情书,

但其中最令人难忘的也许
是这封简短而紧急的信:

“三天后回家。别洗澡。”

(笑声)

拿破仑和约瑟芬都
喜欢紫罗兰。

约瑟芬穿着紫罗兰香味的香水,

在他们结婚的那天带着紫罗兰

,拿破仑

每年都会在他们的周年纪念日送她一束紫罗兰。

约瑟芬去世后,

他在她的坟墓上种下了紫罗兰

,就在流放前,

他回到了那个墓地,

摘了一些花,
把它们埋在一个小盒子里

,一直戴到他去世的那一天。

我发现这太感人了,

我想,我能不能把那个紫罗兰设计
成像约瑟芬一样闻起来?

如果在余下的时间里,

当你去访问她的网站时,

你能闻到约瑟芬的味道
,就像拿破仑爱她一样?

我们能设计出新的哀悼方式,

新的记忆仪式吗?

毕竟,我们设计的
转基因作物

是为了实现利润最大化

、经得起运输的

作物、保质期长的

作物、尝起来甜甜
但能抵抗害虫的作物,

有时是以
牺牲营养价值为代价的。

我们可以利用这些相同的技术
来获得情绪敏感的输出吗?

所以目前在我的实验室里,

我正在研究这样的问题,
是什么让人类闻起来像人类?

事实证明它相当复杂。

您的饮食
、药物、生活方式

等因素都会影响您的气味。

而且我发现我们的
汗水大多是无味的,

但我们的细菌和微生物

组对你的气味、
你的情绪、你的身份

等等负有责任。

你会发出各种各样的分子,

但我们只能下意识地感知。

所以我一直在对

我身体不同部位的细菌进行分类和收集。

在与科学家交谈后,我们想,

也许 Ani 的完美

混合物就像 10% 的锁骨、
30% 的腋下、

40% 的比基尼线等等

,偶尔
我会让其他实验室的研究人员

闻一下我的样本。

听到
身体的气味是如何在身体环境

之外被感知的,这很有趣

我收到了一些反馈,比如

闻起来像花、像鸡肉、

像玉米片、

像牛肉卷。

(笑声)

同时,我培育
了一组食肉植物,

因为它们能够散发出
肉体的气味来吸引猎物

,试图

在我的细菌和这个生物体之间建立这种共生关系。

碰巧
,我在麻省理工学院,在一家酒吧里

,我正在和

一位恰好是化学家
和植物科学家的科学家交谈

,我正在告诉他我的项目

,他就像 ,“嗯,这听起来
像是孤独女性的植物学。”

(笑声)

我不慌不忙地说,“好吧。”

我挑战他。

“我们可以设计出一种
可以爱我的植物吗?”

出于某种原因,
他就像,“当然,为什么不呢?”

所以我们开始了,
我们能不能让植物

像太阳一样朝我生长?

因此,我们正在研究植物中的
机制,例如向光性,

通过产生生长素等激素导致植物向太阳生长,

从而导致细胞
在阴凉处伸长。

而现在,我正在制作
一组

注入这些化学物质的口红

,让我能够根据植物
自身的化学特征与植物互动——

让植物
在我亲吻的地方生长,在我亲吻的地方

开花的植物。
盛开。

通过这些项目,

我提出了一些问题,例如,

我们如何定义自然?

当我们可以重新设计自然的属性时,我们如何定义自然

,何时应该这样做?

我们应该为了利润,为了效用而这样做吗?

我们可以为了情感目的而这样做吗?

生物技术可以
用来创作像音乐一样动人的作品吗?

科学

与其塑造
我们情感景观的能力之间的门槛是什么?

形式追随功能是著名的设计
理念。

好吧,现在,夹
在科学、设计和艺术之间的某个地方,

我要问了

,如果小说告诉事实呢?

那会是什么样的研发实验室,我们会一起

提出什么样的问题

我们经常将技术视为答案,

但作为艺术家和设计师,

我想问,但问题是什么?

谢谢你。

(掌声)