The brain benefits of deep sleep and how to get more of it Dan Gartenberg

What if you could make
your sleep more efficient?

As a sleep scientist,

this is the question
that has captivated me

for the past 10 years.

Because while the lightbulb
and technology have brought about a world

of 24-hour work and productivity,

it has come at the cost

of our naturally occurring
circadian rhythm

and our body’s need for sleep.

The circadian rhythm dictates
our energy level throughout the day,

and only recently we’ve been conducting
a global experiment on this rhythm,

which is putting our sleep health

and ultimately
our life quality in jeopardy.

Because of this,

we aren’t getting the sleep we need,

with the average American
sleeping a whole hour less

than they did in the 1940s.

For some reason,

we decided to wear it as a badge of honor

that we can get by on not enough sleep.

This all adds up to a real health crisis.

Most of us know that poor sleep
is linked to diseases

like Alzheimer’s, cardiovascular disease,

stroke and diabetes.

And if you go untreated
with a sleep disorder like sleep apnea,

you’re more likely
to get many of these illnesses.

But did you know about sleep’s impact
on your mental states?

Poor sleep makes us
make risky, rash decisions

and is a drain
on our capacity for empathy.

When sleep deprivation literally makes us
more sensitive to our own pain,

it’s not so surprising that we have
a hard time relating to others

and just generally
being a good and healthy person

when we’re sleep-deprived.

Scientists are now starting to understand

how not only the quantity

but also the quality of sleep
impacts our health and well-being.

My research focuses

on what many scientists believe
is the most regenerative stage of sleep:

deep sleep.

We now know that generally speaking,

there are three stages of sleep:

light sleep,

rapid eye movement or REM

and deep sleep.

We measure these stages by connecting
electrodes to the scalp, chin and chest.

In light sleep and REM,

our brain waves are very similar
to our brain waves in waking life.

But our brain waves in deep sleep
have these long-burst brain waves

that are very different
from our waking life brain waves.

These long-burst brain waves
are called delta waves.

When we don’t get the deep sleep we need,

it inhibits our ability to learn

and for our cells and bodies to recover.

Deep sleep is how we convert
all those interactions

that we make during the day

into our long-term memory
and personalities.

As we get older,

we’re more likely to lose
these regenerative delta waves.

So in way, deep sleep and delta waves

are actually a marker
for biological youth.

So naturally, I wanted to get
more deep sleep for myself

and I literally tried almost every gadget,
gizmo, device and hack out there –

consumer-grade, clinical-grade,

what have you.

I learned a lot, and I found
I really do need, like most people,

eight hours of sleep.

I even shifted my circadian component

by changing my meals,
exercise and light exposure,

but I still couldn’t find a way
to get a deeper night of sleep …

that is until I met
Dr. Dmitry Gerashchenko

from Harvard Medical School.

Dmitry told me about
a new finding in the literature,

where a lab out of Germany showed
that if you could play certain sounds

at the right time in people’s sleep,

you could actually make sleep
deeper and more efficient.

And what’s more, is that this lab showed

that you actually could improve
next-day memory performance

with this sound.

Dmitry and I teamed up,

and we began working on a way
to build this technology.

With our research lab
collaborators at Penn State,

we designed experiments
in order to validate our system.

And we’ve since received grant funding
from the National Science Foundation

and the National Institute of Health

to develop this deep-sleep
stimulating technology.

Here’s how it works.

People came into the lab

and we hooked them up
to a number of devices,

two of which I have on right here –

not a fashion statement.

(Laughter)

When we detected
that people were in deep sleep,

we played the deep-sleep
stimulating sounds

that were shown
to make them have deeper sleep.

I’m going to demo this sound
for you right now.

(Repeating sound waves)

Pretty weird, right?

(Laughter)

So that sound is actually at the same
burst frequency as your brain waves

when your brain is in deep sleep.

That sound pattern
actually primes your mind

to have more of these
regenerative delta waves.

When we asked participants
the next day about the sounds,

they were completely unaware
that we played the sounds,

yet their brains responded
with more of these delta waves.

Here’s an image of someone’s brain waves
from the study that we conducted.

See the bottom panel?

This shows the sound being played
at that burst frequency.

Now look at the brain waves
in the upper part of the graph.

You can see from the graph

that the sound is actually producing
more of these regenerative delta waves.

We learned that we could
accurately track sleep

without hooking people up to electrodes

and make people sleep deeper.

We’re continuing to develop

the right sound environment
and sleep habitat

to improve people’s sleep health.

Our sleep isn’t
as regenerative as it could be,

but maybe one day soon,

we could wear a small device

and get more out of our sleep.

Thank you.

(Applause)

如果你能让
你的睡眠更有效率呢?

作为一名睡眠科学家,

这是过去 10 年
来一直困扰着我

的问题。

因为虽然灯泡
和技术带来了一个

24 小时工作和生产力的世界,

但它

是以我们自然发生的
昼夜节律

和我们身体对睡眠的需求为代价的。

昼夜节律决定
了我们全天的能量水平

,直到最近我们才开始
对这种节律进行全球实验,

这使我们的睡眠健康

和最终
的生活质量处于危险之中。

正因为如此,

我们没有得到我们需要的睡眠,

美国人的平均
睡眠时间比 1940 年代少了整整一个小时

出于某种原因,

我们决定将它作为荣誉徽章佩戴

,我们可以在睡眠不足的情况下度过难关。

这一切都构成了真正的健康危机。

我们大多数人都知道,睡眠不足

与阿尔茨海默氏症、心血管疾病、

中风和糖尿病等疾病有关。

如果您
患有睡眠呼吸暂停等睡眠障碍而未经治疗,

您更有
可能患上许多此类疾病。

但是你知道睡眠
对你的精神状态的影响吗?

睡眠不足使我们
做出冒险、轻率的决定,


消耗我们的同理心。

当睡眠剥夺从字面上
使我们对自己的痛苦更加敏感时,

我们很难与他人建立联系,

并且在睡眠剥夺时通常
只是一个好人和健康的人,这并不奇怪

科学家们现在开始了解

睡眠的数量和质量如何
影响我们的健康和幸福。

我的研究集中

在许多科学家
认为最具再生能力的睡眠阶段:

深度睡眠。

我们现在知道,一般来说

,睡眠分为三个阶段:

浅睡眠、

快速眼动或快速眼动

和深睡眠。

我们通过将
电极连接到头皮、下巴和胸部来测量这些阶段。

在轻度睡眠和快速眼动中,

我们的
脑电波与清醒时的脑电波非常相似。

但是我们在深度睡眠中的脑电波
有这些长脉冲的脑电波,这些脑电波

与我们清醒时的脑电波非常不同。

这些长脉冲脑电波
被称为δ波。

当我们没有得到我们需要的深度睡眠时,

它会抑制我们的学习能力

以及我们的细胞和身体的恢复能力。

深度睡眠

是我们将白天进行的所有互动

转化为长期记忆
和个性的方式。

随着年龄的增长,

我们更有可能失去
这些再生三角波。

所以在某种程度上,深度睡眠和三角

波实际上
是生物青春的标志。

所以很自然,我想
为自己获得更多的深度睡眠

,我几乎尝试了所有的小工具、小玩意
、设备和黑客——

消费级的、临床级的,

你有什么。

我学到了很多,我发现
我真的需要,像大多数人一样,

八小时的睡眠。

我什至

通过改变我的饮食、
锻炼和光照来改变我的昼夜节律,

但我仍然找不到让睡眠更深的方法

……直到我遇到了

哈佛医学院的 Dmitry Gerashchenko 博士。

德米特里告诉我
文献中的一个新

发现,德国的一个实验室表明
,如果你能

在人们睡眠的正确时间播放某些声音,

你实际上可以让睡眠
更深、更有效率。

更重要的是,这个实验室表明

,你实际上可以用这种声音提高
第二天的记忆性能

德米特里和我合作

,我们开始
研究建立这项技术的方法。

我们
与宾夕法尼亚州立大学的研究实验室合作者一起

设计了
实验来验证我们的系统。

此后,我们获得
了美国国家科学基金会

和美国国立卫生研究院的赠款,

用于开发这种深度睡眠
刺激技术。

这是它的工作原理。

人们走进实验室

,我们将他们连接
到许多设备上,其中

两个我就在这里——

不是时尚宣言。

(笑声)

当我们检测
到人们处于深度睡眠状态时,

我们会播放深度睡眠
刺激声音

,这些声音被证明
可以让他们睡得更深。

我现在要为你演示这个声音

(重复声波)

很奇怪,对吧?

(笑声)

所以当你的大脑处于深度睡眠时,声音实际上
与你的脑电波处于相同的爆发频率

这种声音模式
实际上会让你的

大脑产生更多这些
再生三角波。 第二天,

当我们向
参与者询问这些声音时,

他们完全不
知道我们播放了这些声音,

但他们的大脑却
以更多的这些 delta 波作出反应。


是我们进行的研究中某人脑电波的图像。

看到底部面板了吗?

这显示了
以该突发频率播放的声音。

现在看看
图表上部的脑电波。

从图

中可以看出,声音实际上产生了
更多的这些再生 delta 波。

我们了解到,我们可以
准确地跟踪睡眠,

而无需将人们连接到电极上

,并使人们睡得更深。

我们正在继续

开发合适的声音环境
和睡眠环境,

以改善人们的睡眠健康。

我们的睡眠
没有它可以再生的那么好,

但也许很快有一天,

我们可以戴上一个小设备

,从睡眠中得到更多。

谢谢你。

(掌声)