What happens during a stroke Vaibhav Goswami

Every two seconds, someone somewhere
in the world experiences a stroke.

And one out of every six people will have
one at some point in their lives.

Strokes deprive brain cells of oxygen

and are one of the most
common causes of death

and a leading cause
of preventable disability.

When someone experiences a stroke,
quick medical care is critical,

and can often help avoid
permanent brain damage.

But what causes strokes
in the first place?

And what can doctors do to treat them?

The brain makes up just 2%
of your body’s mass

but consumes more than 20%
of the oxygen in your blood.

That oxygen is carried to the brain
through a system of arteries.

Carotid arteries supply
the front of the brain,

and vertebral arteries supply the back.

These are connected to each other,

and divide into smaller
and smaller vessels

that get billions of neurons
the oxygen they need.

If the blood flow is interrupted,
oxygen delivery stops and brain cells die.

There are two ways this can happen.

Hemorrhagic strokes are when a perforated
vessel allows blood to leak out.

But the more common type
is the ischemic stroke,

when a clot blocks a vessel
and brings blood flow to a halt.

Where do these clots come from?

On rare occasions,
a sudden change in heart rhythm

prevents the upper chambers of the heart
from contracting normally.

This slows down blood flow,

allowing platelets, clotting factors,
and fibrin to stick together.

The clot can be carried up

towards the arteries
and blood vessels supplying the brain

until it gets to one
it can’t squeeze through.

This is called an embolism

and it cuts off the oxygen supply
to all the cells downstream.

The brain doesn’t have pain receptors,
so you can’t feel the blockage itself.

But oxygen deprivation
slows brain function

and can have sudden, noticeable effects.

For example, if the affected area
is responsible for speech,

an individual’s words may be slurred.

If the stroke affects a part of the brain
that controls muscle movement,

it can cause weakness,
often just on one side of the body.

When this happens, the body
will immediately try to compensate

by diverting blood flow
to the affected area,

but this isn’t a perfect solution.

Eventually, the oxygen-deprived cells
will start to die,

leading to brain damage
that may be severe or permanent.

That’s why it’s important to get
medical care as fast as possible.

The first line of treatment
is an intravenous medication

called Tissue Plasminogen Activator,

which can break up the blood clot

and allow blood to flow again
in the compromised artery.

If it’s delivered within a few hours,

this medication greatly increases
the chance of surviving the stroke

and avoiding permanent consequences.

If Tissue Plasminogen Activator
cannot be given

because the patient
is on certain medications,

has history of major bleeding,

or the clot is particularly large,

doctors can perform a procedure
called an endovascular thrombectomy.

Using a fluorescent dye that illuminates
the blood vessels under a strong x-ray,

the physician inserts a long,
thin, flexible tube called a catheter

into an artery in the leg

and maneuvers
it all the way to the blockage.

A retriever is passed
through this catheter.

It expands and anchors into the clot
when it’s just past it.

The catheter then pulls the clot out
when it’s removed.

These treatments need to be delivered
as soon as possible

to preserve brain function,

which means figuring out fast
if someone is having a stroke.

So how can you tell?

Here are three quick things to try:

  1. Ask the person to smile.

A crooked mouth or facial drooping
can indicate muscle weakness.

  1. Ask them to raise their arms.

If one drifts downward, that arm weakness
is also a sign of a stroke.

  1. Ask them to repeat a
    simple word or phrase.

If their speech sounds
slurred or strange,

it could mean that the language area
of their brain is oxygen-deprived.

This is sometimes called the FAST test,
and the T stands for time.

If you see any of those signs,
call emergency services right away.

Lives may depend on it.

每两秒钟,
世界上的某个地方就会有人中风。

每六个人中就有一个人会
在他们生命中的某个时刻拥有一个。

中风会剥夺脑细胞的氧气

,是最
常见的死亡原因

之一,也是可预防残疾的主要原因。

当有人中风时,
快速的医疗护理至关重要,

并且通常可以帮助避免
永久性脑损伤。

但首先是什么导致
中风?

医生可以做些什么来治疗他们?

大脑仅占
身体质量的 2%,

但消耗
了血液中 20% 以上的氧气。

氧气通过动脉系统输送到大脑

颈动脉供应
大脑前部

,椎动脉供应大脑后部。

它们相互连接,

并分成
越来越小的血管

,为数十亿神经元提供
所需的氧气。

如果血流中断,
氧气输送就会停止,脑细胞就会死亡。

发生这种情况有两种方式。

出血性中风是指穿孔的
血管使血液渗出。

但更常见的类型
是缺血性中风,

当凝块阻塞血管
并使血流停止时。

这些凝块是从哪里来的?

在极少数情况下,
心律的突然变化会

阻止心脏的上腔室
正常收缩。

这会减慢血液流动,

使血小板、凝血因子
和纤维蛋白粘在一起。

凝块可以向上

输送到供应大脑的动脉和血管,

直到它到达
无法挤过的地方。

这被称为栓塞

,它会切断
下游所有细胞的氧气供应。

大脑没有痛觉感受器,
所以你感觉不到阻塞本身。

但缺氧
会减慢大脑功能,

并可能产生突然的、明显的影响。

例如,如果受影响的区域
负责说话,

则个人的话语可能会含糊不清。

如果中风
影响控制肌肉运动的大脑部分,

则可能导致虚弱,
通常仅在身体的一侧。

发生这种情况时,身体
会立即尝试

通过将血流转移
到受影响的区域来进行补偿,

但这并不是一个完美的解决方案。

最终,缺氧细胞
将开始死亡,

导致可能严重或永久性的脑损伤。

这就是为什么尽快获得
医疗服务很重要。

第一线治疗
是一种

称为组织纤溶酶原激活剂的静脉注射药物,

它可以分解血凝块

,让血液
在受损动脉中再次流动。

如果它在几个小时内交付,

这种药物会大大增加
中风幸存的机会

并避免永久性后果。

如果

由于
患者服用某些药物、

有大出血史

或凝块特别大而无法给予组织纤溶酶原激活剂,

医生可以进行
称为血管内血栓切除术的手术。 医生

使用
一种在强 X 射线下照亮血管的荧光染料,

将一根称为导管的长而
细的柔性管

插入腿部动脉

,并将
其一直移动到阻塞处。

取回器
穿过该导管。 当

它刚经过凝块时,它会膨胀并固定在凝块中

然后,导管在取出凝块
时将其拉出。

需要尽快提供这些治疗

以保护大脑功能,

这意味着要快速
确定某人是否中风。

那你怎么知道?

这里有三件可以快速尝试的事情:

  1. 让对方微笑。

歪嘴或面部下垂
可能表明肌肉无力。

  1. 请他们举起手臂。

如果一个人向下漂移,那手臂无力
也是中风的征兆。

  1. 让他们重复一个
    简单的单词或短语。

如果他们的讲话听起来
含糊不清或奇怪,

这可能意味着
他们大脑的语言区域缺氧。

这有时被称为 FAST 测试
,T 代表时间。

如果您看到任何这些迹象,
请立即致电紧急服务部门。

生活可能取决于它。