A teen scientists invention to help wounds heal Anushka Naiknaware

Ever since I was a young girl,
I was always fascinated –

(Laughter)

Oh!

(Laughter)

OK, I meant younger and more short.

(Laughter)

If that’s possible to imagine.

But ever since I was a young girl,

I was always fascinated with how
the world worked exactly how it did.

So this, very early on,

led me to the fields
of mathematics and chemistry.

I would keep going further and further,
and as I kept going,

I realized that all the fields
of science are interconnected.

And without one, the others
have little or no value.

So, inspired by Marie Curie
and my local science museum,

I decided to start asking
these questions myself

and engage in my own independent research,

whether it be out
of my garage or my bedroom.

I started reading journal papers,

started doing science competitions,

started participating in science fairs,

doing anything I could

to get the knowledge
that I so desperately wanted.

So while I was studying anatomy
for a competition,

I came across the topic
of something called chronic wounds.

And one thing that stood out
to me was a statistic

that said that the number of people
in the United States with chronic wounds

exceeds the number of people
with breast cancer,

colon cancer, lung cancer
and leukemia, combined.

Hold up.

So what is a chronic wound?

(Laughter)

And why haven’t I heard
about a 5K walk for chronic wounds,

why haven’t I even heard
about a chronic wound in general?

(Laughter)

So after I got past
those preliminary questions,

and one that I will clarify for you,

a chronic wound is essentially
when someone gets a normal wound,

except it fails to heal normally

because the patient has some kind
of preexisting condition,

which in most cases is diabetes.

So more staggering statistics
were to be found

as I kept going on in this research.

In the year 2010 alone,

50 billion dollars were spent worldwide
to treat chronic wounds.

In addition, it’s estimated
that about two percent of the population

will get a chronic wound
at some point in their lifetime.

This was absurd.

So as I started doing more research,

I found that there was a correlation

between the moisture level
inside a wound dressing

and the stage of healing
that the chronic wound would be at.

So I decided, why don’t I design something

to measure the moisture level
within the wound

so this can help doctors and patients
treat their wounds better.

And essentially, expedite
the healing process.

So that’s exactly what I set out to do.

Being a 14-year-old working
out of her garage-turned-lab,

I had a lot of constraints.

Most being that I wasn’t given a grant,
I wasn’t given a lot of money,

and I wasn’t given a lot of resources.

In addition, I had
a lot of criteria, as well.

Since this product would be
readily interacting with the body,

it had to be biocompatible,

it also had to be low-cost,

as I was designing it
and paying for it myself.

It also had to be mass-manufacturable,

because I wanted it to be made
anywhere, for anyone.

Thus, I drafted up a schematic.

What you see on the left hand-side
is the early schematics in my design,

showing both a bird’s-eye view
and also one stacking variant.

A stacking variant means

that the entire product is consisted
of different individual parts

that have to work in unison.

And what’s shown there
is one possible arrangement.

So what exactly is this?

So I had gone on to testing my sensors

and as all scientists have
stumbles along their work,

I also had a couple of problems
in my first generation of sensors.

First of all, I couldn’t figure out

how to get a nanoparticle ink
into a printcheck cartridge

without spilling it all over my carpet.

That was problem number one.

Problem number two was,

I couldn’t exactly control
the sensitivity of my sensors.

I couldn’t scale them up or down,

I couldn’t really do
anything of that sort.

So I wanted something to solve it.

Problem one was easily solved
by some scouting on eBay and Amazon

for syringes that I could use.

Problem two, however,
required a lot more thought.

So this is where this factors in.

So what a space-filling curve does

is it aims to take up all the area it can
within one unit square.

And by writing a computer program,
you can have different iterations

of the different curve,

which increasingly get close
to one unit square,

but never quite reaches there.

So now I could control
the thickness, the size,

I could do whatever I want with it,
and I could predict my results.

So I started constructing my sensors

and testing them more rigorously,

using money that I had gotten
from previous science fair awards.

Lastly, I had to connect this data
in order to be read.

So I interfaced it with a Bluetooth chip,

which you can see here
by the app screenshots on the right.

And what this does is that anyone
can monitor the progress of their wound,

and it can be transmitted
over a wireless connection

to the doctor, the patient
or whoever needs it.

[Continued Testing and Refinement]

So in conclusion, my design
was successful –

however, science never ends.

There’s always something to be done,
something to be refined.

So that’s what I’m currently
in the process of doing.

However, what I learned was

what’s more important
than the actual thing I designed

is an attitude that I had
taken on while doing this.

And that attitude was,

even though I’m a 14-year-old
working in her garage

on something that she doesn’t
completely understand,

I could still make a difference
and contribute to the field.

And that’s what inspired me to keep going,

and I hope it inspires many others
to also do work like this

even though they’re not
very sure about it.

So I hope that’s a message
that you all take on today.

Thank you.

(Applause)

从我还是个小女孩开始,
我就一直很着迷——

(笑声)

哦!

(笑声)

好吧,我的意思是更年轻,更矮。

(笑声)

如果可以想象的话。

但自从我还是个年轻女孩的时候,

我就一直对
这个世界是如何运作的非常着迷。

所以这很早

就把我带到
了数学和化学领域。

我会越走越远
,随着我不断前进,

我意识到所有
科学领域都是相互关联的。

没有一个,其他的
就几乎没有价值。

因此,受居里夫人
和我当地科学博物馆的启发,

我决定自己开始提出
这些问题,

并从事我自己的独立研究,

无论是
在我的车库还是在我的卧室。

我开始阅读期刊论文,

开始参加科学竞赛,

开始参加科学展览,

尽我

所能获得
我迫切想要的知识。

所以当我为一场比赛学习解剖学时

我遇到
了一个叫做慢性伤口的话题。 令

我印象深刻的一件事
是一项统计数据

,表明
美国患有慢性伤口

的人数超过了
患有乳腺癌、

结肠癌、肺癌
和白血病的人数的总和。

耽误。

那么什么是慢性伤口?

(笑声)

为什么我没有
听说过 5K 步行可以治疗慢性伤口,

为什么我什至没有听说
过一般的慢性伤口?

(笑声)

所以在我解决了
这些初步问题之后

,我将为您澄清一个问题

,慢性伤口本质上是
当某人受到正常伤口时,

除非它无法正常愈合,

因为患者有
某种预先存在的状况

, 大多数情况下是糖尿病。

因此,

当我继续进行这项研究时,会发现更多惊人的统计数据。

仅在 2010 年,

全球就花费了 500 亿美元
用于治疗慢性伤口。

此外,据估计
,大约 2% 的人口


在其一生中的某个时候出现慢性伤口。

这是荒谬的。

因此,当我开始进行更多研究时,

我发现

伤口敷料内的水分含量

与慢性伤口的愈合阶段之间存在相关性。

所以我决定,我为什么不设计一些东西

来测量伤口内的水分含量

,这样可以帮助医生和病人
更好地治疗他们的伤口。

本质上,
加快愈合过程。

所以这正是我打算做的。

作为一个 14
岁的女孩,我在车库改造的实验室里工作,

我有很多限制。

最重要的是我没有得到资助,
没有得到很多钱,

也没有得到很多资源。

此外,我也
有很多标准。

由于该产品很
容易与身体相互作用,

因此它必须具有生物相容性,

而且还必须是低成本的,

因为我正在设计
它并自己付费。

它还必须是可大规模制造的,

因为我希望它可以在
任何地方为任何人制造。

因此,我起草了一个示意图。

您在左侧看到的
是我设计中的早期示意图,

显示了鸟瞰图
和一个堆叠变体。

堆叠变体

意味着整个产品由

必须协同工作的不同单独部分组成。

所显示的
是一种可能的安排。

那么这究竟是什么?

所以我继续测试我的传感器

,因为所有
科学家在他们的工作中

都遇到了挫折,
我在第一代传感器中也遇到了一些问题。

首先,我不知道

如何将纳米粒子墨水
装入打印检查墨盒

而不将其洒在我的地毯上。

那是第一个问题。

第二个问题是,

我无法准确控制
传感器的灵敏度。

我不能放大或缩小它们,

我真的不能
做那种事情。

所以我想要一些东西来解决它。

第一个问题很容易
通过在 eBay 和亚马逊上

寻找我可以使用的注射器来解决。

然而,问题二
需要更多的思考。

所以这就是这个因素的所在。

所以空间填充曲线的作用

是它旨在占据
一个单位正方形内的所有区域。

通过编写一个计算机程序,
你可以对不同的曲线进行不同的迭代

这些迭代越来越
接近一个单位平方,

但永远不会完全到达那里。

所以现在我可以
控制厚度和大小,

我可以用它做任何我想做的事情
,我可以预测我的结果。

所以我开始构建我的传感器

并更严格地测试它们,

使用我
从之前的科学博览会奖项中获得的资金。

最后,我必须连接这些
数据才能被读取。

所以我将它与蓝牙芯片连接起来

,您可以
通过右侧的应用程序屏幕截图看到它。

这样做的目的是任何人都
可以监控伤口的进展,

并且可以
通过无线连接

将其传输给医生、患者
或任何需要它的人。

[继续测试和改进

] 总而言之,我的设计
是成功的——

然而,科学永无止境。

总有一些事情要做,
有些事情需要改进。

这就是我
目前正在做的事情。

然而,我学到的是

比我设计的实际东西更重要的

是我
在做这件事时所采取的态度。

这种态度是,

即使我是一个 14 岁的女孩
,在她的车库里工作

她并不
完全理解的事情,

我仍然可以有所作为
并为这个领域做出贡献。

这就是激励我继续前进的原因

,我希望它能激励许多其他
人也从事这样的工作,

即使他们
对此不太确定。

所以我希望这
是你们今天都接受的信息。

谢谢你。

(掌声)