Unintended consequences Edward Tenner

I didn’t always love unintended

consequences but I really learned to

appreciate them I’ve learned that

they’re really the essence of what makes

for progress even when they seem to be

terrible and I’d like to review just how

unintended consequences play the part

that they do let’s go to 40,000 years

before the present to the time of the

cultural explosion when music art

technology so many of the things that

we’re enjoying today so many of the

things that are being demonstrated at

Ted were born and the anthropologist

Randall White has made a very

interesting observation that if our

ancestors forty thousand years ago had

been able to see what they had done they

wouldn’t have really understood it they

were responding to immediate concerns

they were making it possible for us to

do what they do and yet they didn’t

really understand how they did it

now let’s advance to 10,000 years before

the present and this is when it really

gets interesting what about the

domestication of grains what about the

origins of Agriculture

what would our ancestors 10,000 years

ago have said if they really had

technology assessment and I can just

imagine the committee’s reporting back

to them on where agriculture was going

to take humanity at least in the next

few hundred years it was really bad news

first of all worse nutrition maybe

shorter lifespans it was simply awful

for women the skeletal remains from that

period have shown that they were

grinding grain morning noon and night

and politically it was awful it was the

beginning of a much higher degree of

inequality among people if there had

been rational

technology assessment then I think they

very well might have said let’s call the

whole thing off even now our choices are

having unintended effects historically

for example chopsticks according to one

Japanese anthropologist who wrote a

dissertation about it at the University

of Michigan resulted in long-term

changes in the dentition in the teeth of

the Japanese public and we are also

changing our teeth right now there there

is evidence that the human mouth and

teeth are growing smaller all the time

that’s not necessarily a bad unintended

consequences but I think from the point

of view of a Neanderthal there would

have been a lot of disapproval of the

wimpish choppers that we now have so

these things are kind of relative to

where you’re you or your your ancestors

happen to stand in the ancient world

there was a lot of respect for

unintended consequences there was a very

healthy sense of caution reflected in

the tree of knowledge in Pandora’s Box

and especially in the myth of Prometheus

that’s been so important in recent

metaphors about technology and that’s

all very true the physicians of the

ancient world especially the Egyptians

who started medicine as we know it were

very conscious of what they could and

couldn’t treat and the translations of

the surviving text say this I will not

treat this I cannot treat they were very

conscious so were the followers of

Hippocrates the Hippocratic manuscripts

also repeatedly according to recent

studies so how important it is not to do

harm

more recently Harvey Cushing who really

developed neurosurgery as we know it who

changed it from a field of medicine that

had a majority of deaths resulting from

surgery to one in which there was a

hopeful outlook he was very conscious

that he was not always going to do the

right thing but he did his best and he

kept meticulous records that let him

transform

that branch of medicine now if we look

forward a bit

to the 19th century we find a new style

of technology what we find is no longer

simple tools but systems we find more

and more complex arrangements of

machines that make it harder and harder

to diagnose what’s going on and the

first people who saw that were the

telegraphers of the mid 19th century who

were the original hackers Thomas Edison

would have been very very comfortable in

the atmosphere of a software firm today

and these hackers have a word for those

mysterious bugs and telegraph systems

that they called bugs that was the

origin of the word bug this

consciousness though was a little slow

to seep through the general population

even people who were very very

well-informed Samuel Clemens Mark Twain

was a big investor in the most complex

machine of all times at least until 1918

registered with the US Patent Office

that was the page typesetter the page

type setter had 18,000 parts the patent

had 64 pages of text and 271 figures it

was such a beautiful machine because it

did everything that a human being did

and setting type including returning the

type to its place which was a very

difficult thing and Mark Twain who knew

all about typesetting really was was

smitten by this machine unfortunately he

was smitten in more ways than one

because it made him bankrupt and he had

to tour the world speaking to to recoup

his money and this was an important

thing about 19th century technology that

all these relationships among parts

could make the most brilliant idea fall

apart even when judged by the most

expert people now there was something

else though in the early 20th century

that made things even more complicated

and that was that safety technology

itself could be a source of danger the

lesson of the Titanic for

the contemporaries was that you must

have enough lifeboats for everyone on

the ship and this was the result of the

tragic loss of lives of people who could

not get into them however there was

another pace the Eastland a ship that

capsized in Chicago Harbor in 1915 and

it killed 841 people that was 14 more

than the passenger toll of the Titanic

the reason for it in part was the extra

lifeboats that were added that made this

already unstable ship even more unstable

and that again proves that when you’re

talking about unintended consequences

it’s not that easy to know the right

lessons to draw it’s it’s really a

question of the system how the ship was

loaded the ballast and many other things

so the 20th century then saw how much

more complex reality was but it also saw

a positive side it saw that invention

could actually benefit from emergencies

it could it could benefit from tragedies

and my favorite example of that which is

not really widely known as a

technological miracle but it may be one

of the greatest of all times was the

scaling up of penicillin in the Second

World War penicillin was discovered in

1928 but even by 1940 no commercially

and medically useful quantities of it

were being produced a number of

pharmaceutical companies were working on

it

they were working on it independently

and they weren’t getting anywhere and

the government Research Bureau brought

representatives together and told them

that this is something that has to be

done and not only did they do it but

within two years they scaled up

penicillin from preparation in 1-litre

flasks to ten thousand gallon vats that

was how quickly penicillin was produced

and became one of the greatest medical

advance

of all time in the Second World War to

the existence of solar radiation was

demonstrated by studies of interference

that was detected by the radar stations

of Great Britain so there were benefits

in calamities benefits to pure science

as well as to applied science and

medicine now when we come to the period

after the Second World War

unintended consequences get even more

interesting and my favorite example of

that occurred beginning in 1976 when it

was discovered that the bacteria causing

Legionnaires disease had always been

present in natural waters but it was the

precise temperature of the water in

heating ventilating and air-conditioning

systems that raised the right

temperature for the maximum reproduction

of Legionella bacillus well technology

to the rescue and so a chemist got to

work and they developed a bactericide

that became widely used in those systems

but something else happened in the early

1980s and that was that there was a

mysterious epidemic of failures of tape

drives all over the United States and

IBM which made them just didn’t know

what to do they commissioned a group of

their best scientists to investigate and

what they found was that all these tape

drives were located near ventilation

ducts what happened was the bactericide

was formulated with many traces of 10

and these tin particles were deposited

on the tape heads and were crashing the

tape heads so they reformulated the

bactericide but what’s interesting to me

is that this was the first case of a

mechanical device suffering at least

indirectly from a human disease so it

shows that we’re really all in this

together

in fact it also shows something

interesting that although our

capabilities and technology have been

expanding geometrically unfortunately

our ability to model their long term

behavior which has also been increasing

has been increasing only arithmetic aliy

so one of the characteristic problems of

our time is how to close this gap

between capabilities and foresight one

other very positive consequence of 20th

century technology though was the way in

which other kinds of calamities could

lead to positive advances there are two

historians of business at the University

of Maryland

Brent Goldfarb and David Kirsch who have

done some extremely interesting work

much of it still unpublished on the

history of major innovations they have

combined the list of major innovations

and they’ve discovered that the greatest

number the greatest decade for

fundamental innovations as reflected in

all of the lists that others have made a

number of lists that they emerged was

the Great Depression and nobody knows

just why this was so but one story can

reflect something of it it was the

origin of the Xerox copier which

celebrated its fiftieth anniversary last

year and Chester Carlson the inventor

was a patent attorney he really was not

intending to to work in in patent

research but he couldn’t really find an

alternative technical job so this was

the best job he could get he was upset

by the low quality and high cost of

existing patent reproductions and so he

started to develop a system of dry

photocopying which he patented in the

late 1930s and which became the first

dry photocopier that was commercially

practical in 1960 so we see that

sometimes as a result of these

dislocations as a result of people

leaving

their original intended career and going

into something else where their

creativity could make a difference that

depressions and all kinds of other

unfortunate events can have a

paradoxically stimulating effect on

creativity what does this mean it means

I think that we’re living in a time of

unexpected possibilities

think of the financial world for example

the mentor of Warren Buffett Benjamin

Graham developed his system of value

investing as a result of his own losses

in the 1929 crash and he published that

book in the early 1930s and the book

still exists in further editions and is

still a fundamental text book so many

important creative things can happen

when people learn from disasters now

think of the large and small plagues

that we have now bedbugs

killer bees spam and it’s very possible

that the solutions to those will really

extend well beyond the immediate

question if we think for example of

Louis Pasteur who in the 1860s was asked

to study the diseases of silkworms for

the silk industry and his discoveries

were really the beginning of the germ

theory of disease so very often some

kind of disaster sometimes the

consequence for example of over

cultivation of silkworms which was a

problem in Europe at the time can be the

key to something much bigger so this

means that we need to take a different

view of unintended consequences we need

to take a really positive view we need

to see what they can do for us we need

to learn from those figures that I’ve

mentioned we need to learn for example

from dr. Cushing who killed patients in

the course of his early operations he

had to have some errors he had to have

some mistakes and he learned

meticulously from his mistakes and as a

result when we say this isn’t brain

surgery that pays tribute

how difficult it was for anyone to learn

from their mistakes in a field of

medicine that was considered so

discouraging in its prospects and we can

also remember how the pharmaceutical

companies were willing to pool their

knowledge to share their knowledge in

the face of an emergency

which they hadn’t really been for years

and years they might have been able to

do it earlier the message then for me

about unintended consequences is chaos

happens

let’s make better use of it thank you

very much

我并不总是喜欢意想不到的

后果,但我真的

学会了欣赏它们

他们所做的部分让我们回到

现在之前的 40,000 年,直到

文化爆炸时期,当时音乐艺术

技术

我们今天正在享受的许多

东西,在 Ted 展示的许多东西

都诞生了, 人类学家

兰德尔·怀特(Randall White)做了一个非常

有趣的观察,如果我们的

祖先在四万

年前能够看到他们所做的事情,他们

就不会真正理解它,他们

正在回应眼前的担忧,

他们让我们有可能

做些什么 他们这样做了,但他们并不

真正了解他们是如何做到的

现在让我们前进到现在之前的一万年

,这才是真正

有趣的

时候 谷物的

起源 农业的起源

10,000 年前我们的祖先会怎么

说,如果他们真的有

技术评估,我

可以想象委员会

向他们报告

至少在接下来的几百年内农业将把人类带到哪里

年 这真的是个坏消息

首先是更糟糕的营养 可能

更短的寿命 这对女性来说简直太糟糕

了 那个时期的骨骼残骸

表明她们

每天早午晚都在磨谷物

政治上这太糟糕了 这

是一个更高的开始

如果有合理的技术评估,人们之间的不平等程度,

那么我认为他们

很可能

会说,即使现在我们的选择

在历史上也会产生意想不到的影响

,例如筷子,一位

日本人类学家写了

一篇关于它的论文 密歇根大学

的研究

导致牙列的长期变化

日本公众的牙齿,我们现在也在

换牙

我们现在拥有的懦弱直升机有很多不赞成,所以

这些事情

与你的位置或你的祖先

碰巧站在古代世界

有关,对

意想不到的后果有很多尊重。

潘多拉魔盒中的知识树

,尤其是普罗米修斯的神话

中反映

了非常健康的谨慎感

非常清楚他们可以

处理和不能处理的内容

,幸存文本的翻译说我不会

处理这个 我不能认为他们非常

有意识

,希波克拉底手稿的追随者

也是如此,根据最近的研究,希波克拉底手稿也反复进行,

所以最近不造成伤害是多么重要

哈维库欣谁真正

开发了我们所知道的神经外科,他

从一个领域改变了它

大部分死于

手术的药物变成了

前景充满希望的药物,他非常

清楚自己并不总是会做

正确的事情,但他尽了最大的努力,并

保留了细致的记录,让他

改变了

那个分支 现在的医学如果我们

稍微展望

一下 19 世纪,我们会发现一种新

的技术风格,我们发现的不再是

简单的工具,而是系统我们发现

越来越复杂的机器排列,

这使得

诊断正在发生的事情变得越来越困难

第一个看到的人是

19 世纪中期的电报员,他们

是最初的黑客托马斯·爱迪生(Thomas Edison)

会非常非常com 在

今天一家软件公司的氛围中

,这些黑客对那些

神秘的错误和电报系统有一个词

,他们称之为错误,这就是

错误这个词的起源,

尽管这种意识

在普通人群中渗透的速度有点慢,

即使是那些 消息

灵通的塞缪尔克莱门斯马克吐温

是有史以来最复杂机器的大投资者

,至少在 1918 年之前

在美国专利局注册

是页面排版机页面

排版机有 18,000 个零件,专利

有 64 页 文本和 271 个数字,这

是一台非常漂亮的机器,因为它

完成了人类所做的一切

和设置类型,包括将类型返回

到它的位置,这是一件非常

困难的事情,真正了解排版的马克吐温

被这台机器迷住了 不幸的是,他

受到的打击不止一种,

因为这使他破产了,他

不得不环游世界并与之交谈以收回

他的钱。 这是

关于 19 世纪技术的一件重要的事情,即

所有这些部件之间的关系

可能会使最出色的想法

崩溃,即使在最

专业的人的判断下,现在还有其他

事情,尽管在 20 世纪初

,事情变得更加复杂

和 那就是安全技术

本身可能是危险的来源

泰坦尼克号

给同时代人的教训是,您

必须为船上的每个人提供足够的救生艇

,这是

无法进入的人悲惨丧生的结果

然而,他们

又迈出了一步,1915 年,一艘在芝加哥港倾覆的船在东部地区发生了另一次

事故

,造成 841 人死亡,

比泰坦尼克号的乘客死亡人数多 14 人,

部分原因是增加了额外的

救生艇,这

已经 不稳定的船更不稳定

,这再次证明当您

谈论意外后果

时,要知道正确的事情并不容易

吸取的教训 这实际上是一个

系统问题,船舶如何

装载压载物和许多其他东西,

所以 20 世纪看到了

现实有多么复杂,但它也看到

了积极的一面,它看到

发明实际上可以从紧急情况中受益

它可能会从悲剧中受益,

而我最喜欢的例子是,虽然

没有真正广为人知的是

技术奇迹,但它可能是

有史以来最伟大的例子之一,就是

第二次世界大战中青霉素的扩大规模 青霉素于

1928 年被发现 但即使到了 1940 年,也没有生产出商业

和医学上有用的

数量,许多

制药公司都在研究

它,

他们在独立研究

,但一无所获

,政府研究局

召集代表告诉他们

,这 是必须

要做的事情,他们不仅做到了,而且

在两年内他们

从prepa扩大了青霉素的规模 在 1 升

烧瓶中配给一万加仑大桶的配给量

是青霉素的生产速度,

并成为第二次世界大战中太阳辐射存在史上最伟大的医学

进步

之一

英国的雷达站因此

对纯科学

以及应用科学和

医学都有好处,当我们进入

第二次世界大战后的时期时,

意想不到的后果变得更加

有趣,而我最喜欢的例子

开始发生 1976

年发现导致

军团病的细菌一直

存在于天然水中,但正是

加热通风和空调

系统中的水的精确温度提高了

军团杆菌最大繁殖的合适温度井技术

为了救援,一位化学家开始

工作,他们开发了一种细菌

在这些系统中广泛使用的杀毒剂,

但在 1980 年代初期发生了其他事情

,那就是在美国和 IBM 各地都

出现了磁带驱动器故障的神秘流行病,

这让他们不知道

他们委托他们做什么 一组

他们最优秀的科学家进行调查,

他们发现所有这些磁带

驱动器都位于通风

管道附近发生的事情是

杀菌剂配方中含有许多痕量的 10

,这些锡颗粒沉积

在磁带头上并正在破坏

磁带 头,所以他们重新配制了

杀菌剂,但对我来说有趣的

是,这是第一个

机械设备至少

间接遭受人类疾病的案例,所以它

表明我们真的在一起

,事实上它也表明了一些

有趣的事情 尽管我们的

能力和技术一直

在以几何级数扩展,但不幸的是,

我们模拟其长期

行为的能力 w 它也一直在增加,

一直在增加,

所以

我们这个时代的一个典型问题是如何缩小

能力和远见之间的差距

20 世纪技术的另一个非常积极的结果,

尽管

它是其他类型的灾难可能发生的方式

带来积极的进步

马里兰大学的两位商业历史学家

Brent Goldfarb 和 David Kirsch

做了一些非常有趣的工作,其中

大部分尚未发表在

重大创新的历史上,他们

结合了重大创新的清单

,他们已经 发现

其他人列出的

许多列表中反映的所有基本创新的最大十年

是大萧条,没有人

知道为什么会这样,但一个故事可以

反映它的一些东西 是去年庆祝成立五十

周年的施乐复印机的起源

, 发明者切斯特·卡尔森

是一名专利代理人,他真的不

打算从事专利研究工作,

但他真的找不到

替代的技术工作,所以这是

他能找到的最好的工作,他

对低质量和高成本感到不安

现有的专利复制品,因此他

开始开发一种干式

复印系统,他在 1930 年代后期申请了专利,

并在 1960 年成为第一台

商业实用的干式复印机,

因此我们看到,

有时由于这些

错位, 人们

离开

他们最初的预期职业并

进入其他领域,他们的

创造力可以产生影响,

抑郁症和其他各种

不幸的事件可能对创造力产生

矛盾的刺激作用

这是什么意思这意味着

我认为我们生活在一个

意想不到的可能性的时候

想想金融世界例如

沃伦巴菲特的导师本

杰明格雷厄姆开发了他的sy

由于他

在 1929 年的崩盘中遭受损失而成为价值投资的根源,他

在 1930 年代初出版了那本书,这本书

仍然存在于进一步的版本中,

仍然是一本基础教科书,所以

当人们从中学习时,会发生许多重要的创造性事情 灾难现在

想到

我们现在有的大大小小的瘟疫臭虫

杀手蜜蜂垃圾邮件如果我们

以 1860 年代被要求研究的路易斯巴斯德为例

丝绸业的蚕病

和他的

发现确实

是疾病细菌理论的开端,因此经常会发生

某种灾难,有时甚至

是过度

种植蚕的后果,这

在当时是欧洲的一个问题。

更重要的事情的关键,所以这

意味着我们需要

对意想不到的后果采取不同的看法,我们

需要采取真正积极的看法 我们

需要看看他们能为我们做些什么我们需要

从我提到的那些数字中

学习我们需要从例如博士那里学习

。 库欣在早期手术过程中杀死了病人,

他必须

犯一些错误,他必须犯一些错误,他

从错误中一丝不苟地吸取了教训,

因此,当我们说这不是

脑部手术时,

它是多么困难 任何人都可以

从他们在一个

被认为

前景如此令人沮丧的医学领域的错误中吸取教训,我们

还记得制药

公司是如何愿意汇集他们的

知识以

在面对他们没有的紧急情况时分享他们的知识

真的已经好几年了

,他们可能已经能够

更早地做到这一点,然后对我来说,

关于意外后果的信息是混乱

发生了

让我们更好地利用它,

非常感谢