Aphasia The disorder that makes you lose your words Susan WortmanJutt

Language is an essential part of our lives
that we often take for granted.

With it, we can communicate our thoughts
and feelings,

lose ourselves in novels,

send text messages,

and greet friends.

It’s hard to imagine being unable
to turn thoughts into words.

But if the delicate web of language
networks in your brain

became disrupted by stroke,
illness, or trauma,

you could find yourself truly
at a loss for words.

This disorder, called aphasia,
can impair all aspects of communication.

People who have aphasia remain
as intelligent as ever.

They know what they want to say,

but can’t always get their words
to come out correctly.

They may unintentionally use
substitutions called paraphasias,

switching related words,
like saying “dog” for “cat,”

or words that sound similar,
such as “house” for “horse.”

Sometimes, their words may even be
unrecognizable.

There are several types of aphasia
grouped into two categories:

fluent, or receptive, aphasia

and non-fluent, or expressive, aphasia.

People with fluent aphasia may have
normal vocal inflection

but use words that lack meaning.

They have difficulty comprehending
the speech of others

and are frequently unable to recognize
their own speech errors.

People with non-fluent aphasia,
on the other hand,

may have good comprehension

but will experience long hesitations
between words and make grammatical errors.

We all have that tip-of-the-tongue feeling
from time to time

when we can’t think of a word,

but having aphasia can make it hard
to name simple, everyday objects.

Even reading and writing can be difficult
and frustrating.

So how does this language loss happen?

The human brain has two hemispheres.

In most people, the left hemisphere
governs language.

We know this because in 1861,

the physician Paul Broca studied a patient

who lost the ability to use all
but a single word, “tan.”

During a postmortem study
of that patient’s brain,

Broca discovered a large lesion
in the left hemisphere

now known as Broca’s area.

Scientists today believe that Broca’s area
is responsible in part for naming objects

and coordinating the muscles
involved in speech.

Behind Broca’s area is Wernicke’s area
near the auditory cortex.

That’s where the brain attaches
meaning to speech sounds.

Damage to Wernicke’s area impairs the
brain’s ability to comprehend language.

Aphasia is caused by injury to one or
both of these specialized language areas.

Fortunately, there are other areas
of the brain

which support these language centers

and can assist with communication.

Even brain areas that control movement
are connected to language.

FMRI studies found that when we hear
action words, like “run” or “dance,”

parts of the brain responsible
for movement light up

as if the body was actually running
or dancing.

Our other hemisphere contributes
to language, too,

enhancing the rhythm and intonation
of our speech.

These non-language areas sometimes
assist people with aphasia

when communication is difficult.

So how common is aphasia?

Approximately 1 million people
in the U.S. alone have it,

with an estimated 80,000 new cases
per year.

About one-third of stroke survivors
suffer from aphasia

making it more prevalent
than Parkinson’s disease

or multiple sclerosis,

yet less widely known.

There is one rare form of aphasia called
primary progressive aphasia, or PPA,

which is not caused by stroke
or brain injury,

but is actually a form of dementia

in which language loss
is the first symptom.

The goal in treating PPA is to maintain
language function for as long as possible

before other symptoms of dementia
eventually occur.

However, when aphasia is acquired
from a stroke or brain trauma,

language improvement may be achieved
through speech therapy.

Our brain’s ability to repair itself,
known as brain plasticity,

permits areas surrounding
a brain lesion

to take over some functions during
the recovery process.

Scientists have been conducting
experiments using new forms of technology,

which they believe may encourage brain
plasticity in people with aphasia.

Meanwhile, many people with aphasia
remain isolated,

afraid that others won’t understand
them or give them extra time to speak.

By offering them the time and flexibility
to communicate in whatever way they can,

you can help open the door
to language again,

moving beyond the limitations of aphasia.

语言是我们生活中必不可少的一部分
,我们常常认为这是理所当然的。

有了它,我们可以交流自己的想法
和感受,

沉浸在小说中,

发短信,

和朋友打招呼。

很难想象
无法将想法变成文字。

但是,如果你大脑中微妙的语言网络

因中风、
疾病或创伤而中断,

你会发现自己
真的不知所措。

这种称为失语症的疾病
会损害交流的各个方面。

失语症患者仍然
像以往一样聪明。

他们知道自己想说什么,

但并不总是能正确说出自己的话

他们可能会无意中使用
称为 paraphasias 的替代词,

转换相关的词,
比如用“狗”代替“猫”

或听起来相似的词,
比如用“房子”代替“马”。

有时,他们的话甚至可能
无法辨认。

有几种类型的失语症
分为两类:

流利性或接受性失语症

和非流利性或表达性失语症。

流利的失语症患者可能有
正常的声调变化,

但使用缺乏意义的词。

他们难以理解
他人的讲话,

并且经常无法识别
自己的讲话错误。 另一方面,

患有非流利性失语症的人

可能具有良好的理解力,

但会在单词之间经历长时间的犹豫
并犯语法错误。

当我们想不出一个词时,我们都会时不时地产生舌尖上的感觉,

但是失语会使
简单的日常物品难以命名。

即使是阅读和写作也可能很困难
和令人沮丧。

那么这种语言损失是如何发生的呢?

人脑有两个半球。

在大多数人中,左脑
掌管语言。

我们之所以知道这一点,是因为 1861 年

,医生保罗·布罗卡 (Paul Broca) 研究了一名患者

,该患者失去了使用
“棕褐色”这个词的能力。


对该患者大脑的尸检研究中,

布罗卡在左半球发现了一个大病变

现在称为布罗卡区。

今天的科学家认为,布罗卡
区部分负责命名物体

和协调与
说话有关的肌肉。

Broca 区后面是
靠近听觉皮层的 Wernicke 区。

这就是大脑
赋予语音意义的地方。

韦尼克区受损会损害
大脑理解语言的能力。

失语症是由
这些专业语言区域中的一个或两个受伤引起的。

幸运的是,大脑中还有其他区域

支持这些语言中心

并可以协助沟通。

甚至控制运动的大脑区域
也与语言有关。

FMRI 研究发现,当我们听到
“跑步”或“跳舞”等动作词时,

负责运动的大脑部分会
亮起,

就好像身体真的在跑步
或跳舞一样。

我们的另一半球
也有助于语言,

增强我们说话的节奏和
语调。 当沟通困难时,

这些非语言领域有时会
帮助失语症患者

那么失语症有多常见?

仅在美国就有大约 100 万人

患有这种疾病,估计每年有 80,000 例新病例

大约三分之一的中风幸存者
患有失语症,

使其
比帕金森病

或多发性硬化症

更普遍,但鲜为人知。

有一种罕见的失语症称为
原发性进行性失语症或 PPA,

它不是由中风
或脑损伤引起的,

但实际上是一种

以语言丧失
为首发症状的痴呆症。

治疗 PPA 的目标是在最终出现

痴呆的其他症状之前尽可能长时间地保持语言功能

然而,当中
风或脑外伤导致失语时,

可以通过语言治疗来改善语言

我们的大脑自我修复的能力,
称为大脑可塑性,

允许大脑病变周围的区域

在恢复过程中接管某些功能

科学家们一直在
使用新形式的技术进行实验

,他们认为这可能会促进
失语症患者的大脑可塑性。

与此同时,许多失语症患者
仍然与世隔绝,

害怕别人不理解
他们或给他们额外的时间说话。

通过为他们提供
以任何方式进行交流的时间和灵活性,

您可以帮助他们
再次打开语言之门,

超越失语症的限制。